7608-44-8

Basic information

• Product Name: artocarpin
• Synonyms: artocarpin;2',4',5-Trihydroxy-6-(3-methyl-1-butenyl)-3-(3-methyl-2-butenyl)-7-methoxyflavone;2',4',5-Trihydroxy-7-methoxy-6-(3-methyl-1-butenyl)-3-(3-methyl-2-butenyl)flavone;NSC 241010
• CAS NO: 7608-44-8
• Molecular Formula: C₂₆H₂₈O₆
• Molecular Weight: 436.5
• Mol File: 7608-44-8.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 667.1±55.0 °C(Predicted)
• Appearance: /
• Density: 1.242±0.06 g/cm3(Predicted)
• PKA: 6.38±0.40(Predicted)
• CAS DataBase Reference: artocarpin(CAS DataBase Reference)
• NIST Chemistry Reference: artocarpin(7608-44-8)
• EPA Substance Registry System: artocarpin(7608-44-8)

Safety Data

• Hazardous Substances Data: 7608-44-8(Hazardous Substances Data)

Usage

Description

Artocarpin is a trihydroxyflavone that is characterized by the presence of hydroxy groups at positions 5, 2', and 4', a methoxy group at position 7, a prenyl group at position 3, and a (1E)-3-methylbut-1-enyl group at position 6. It is isolated from Artocarpus heterophyllus and Artocarpus integrifolia and has been found to exhibit antineoplastic activity.

Uses

Used in Pharmaceutical Industry:
Artocarpin is used as an antineoplastic agent for its potential cancer-fighting properties. It is being studied for its ability to target and inhibit the growth of cancer cells, making it a promising candidate for the development of new cancer treatments.
Used in Drug Discovery and Development:
Artocarpin is used as a lead compound in drug discovery and development efforts. Its unique chemical structure and biological activity make it a valuable starting point for the design and synthesis of new drugs targeting various diseases, including cancer.
Used in Cancer Research:
Artocarpin is used as a research tool in cancer research to better understand the molecular mechanisms underlying its antineoplastic activity. This knowledge can help researchers identify new therapeutic targets and develop more effective cancer treatments.

Upstream product

• 5916-10-9 (E)-2-(2,4-dimethoxyphenyl)-5-hydroxy-7-methoxy-6-(3-methylbut-1-en-1-yl)-3-(3-methylbut-2-en-1-yl)-4H-chromen-4-one 
• 1443276-27-4 (E)-5-hydroxy-2-(2-hydroxy-4-methoxyphenyl)-7-methoxy-6-(3-methylbut-1-en-1-yl)-3-(3-methylbut-2-en-1-yl)-4H-chromen-4-one 
• 1443276-28-5 (E)-5-hydroxy-2-(4-hydroxy-2-methoxyphenyl)-7-methoxy-6-(3-methylbut-1-en-1-yl)-3-(3-methylbut-2-en-1-yl)-4H-chromen-4-one 
• 1443276-29-6 (E)-5-hydroxy-7-methoxy-2-(4-methoxy-2-((4-methoxybenzyl)oxy)phenyl)-6-(3-methylbut-1-en-1-yl)-3-(3-methylbut-2-en-1-yl)-4H-chromen-4-one 
• 1443276-30-9 (E)-5-hydroxy-2-(4-hydroxy-2-((4-methoxybenzyl)oxy)phenyl)-7-methoxy-6-(3-methylbut-1-en-1-yl)-3-(3-methylbut-2-en-1-yl)-4H-chromen-4-one 
• 1443276-31-0 (E)-5-hydroxy-7-methoxy-2-(2-methoxy-4-((4-methoxybenzyl)oxy)phenyl)-6-(3-methylbut-1-en-1-yl)-3-(3-methylbut-2-en-1-yl)-4H-chromen-4-one 
• 832-58-6 1-(2,4,6-trimethoxyphenyl)ethanone 
• 1443276-18-3 1-(3-acetyl-2-hydroxy-4,6-dimethoxyphenyl)-3-methyl-1-butanone 
• 621-23-8 1,2,3-trimethoxybenzene 
• 1443276-19-4 2-acetyl-3,5-dimethoxy-6-(3-methylbutanoyl)phenyl 2,4-dimethoxybenzoate 
• 1443276-21-8 1-(2,6-dihydroxy-4-methoxy-3-(3-methylbutanoyl)phenyl)-3-(2,4-dimethoxyphenyl)-2-(3-methylbut-2-en-1-yl)propane-1,3-dione 
• 1443276-24-1 2-(2,4-dimethoxyphenyl)-5-hydroxy-7-methoxy-3-(3-methylbut-2-en-1-yl)-6-(3-methylbutanoyl)-4H-chromen-4-one 
• 1443276-25-2 2-(2,4-dimethoxyphenyl)-5-hydroxy-6-(1-hydroxy-3-methylbutyl)-7-methoxy-3-(3-methylbut-2-en-1-yl)-4H-chromen-4-one 

Relevant articles and documents

Total syntheses of norartocarpin and artocarpin

The total syntheses of norartocarpin and artocarpin, two biologically interesting natural flavonoids with two regioisomeric isoprenyl side chains, were achieved for the first time via a linear reaction sequence of 9 and 12 steps with the overall yields of