76143-84-5Relevant articles and documents
Synthesis and SAR Studies of Isoquinoline and Tetrahydroisoquinoline Derivatives as Melatonin Receptor Ligands
Ettaoussi, Mohamed,Laversin, Amélie,Vreulz, Brandon,Rami, Marouane,Lebegue, Nicolas,Delagrange, Philippe,Caignard, Daniel Henri,Melnyk, Patricia,Liberelle, Maxime,Yous, Sa?d
, (2021/12/03)
In our constant search for new successors of agomelatine, we report herein a new series of compounds resulting from bioisosteric modulation of the naphthalene ring. The isoquinoline and tetrahydroisoquinoline derivatives were synthesized and pharmacologic
Reaction of isoquinoline 2-oxides with methylsulfinylmethyl carbanion
Takeuchi,Masuda,Hamada
, p. 2602 - 2604 (2007/10/02)
7-Methoxy-3-methylsulfonyl-3H-benz[d]azepine (5) and 2-deuterio-3-(methyl-d3)-sulfonyl-3H-benz[d]azepine (14) were obtained from the reaction of the corresponding isoquinoline 2-oxides with methylsulfinylmethyl carbanion. A revised reaction mechanism is proposed on the basis of the results obtained by use of deuterated dimethyl sulfoxide-d6.
Spasmolytic agents. I. Aminoalcohol esters having a phenethylamine-like moiety
Kanao,Hashizume,Ichikawa,Irie,Satoh,Isoda
, p. 180 - 188 (2007/10/02)
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