761458-01-9

Basic information

• Product Name: 6-bromo-2-isopropyl-3,1-benzoxazin-4-one
• CAS NO: 761458-01-9
• Molecular Formula: C₁₁H₁₀BrNO₂
• Molecular Weight: 268.1066
• Mol File: 761458-01-9.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 6-bromo-2-isopropyl-3,1-benzoxazin-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 6-bromo-2-isopropyl-3,1-benzoxazin-4-one(761458-01-9)
• EPA Substance Registry System: 6-bromo-2-isopropyl-3,1-benzoxazin-4-one(761458-01-9)

Safety Data

• Hazardous Substances Data: 761458-01-9(Hazardous Substances Data)

Upstream product

• 97-72-3 2-Methylpropionic anhydride 
• 5794-88-7 5-Bromo-2-aminobenzoic acid 
• 79-30-1 isobutyryl chloride 

Downstream Products

• 875269-98-0 tert-butyl (3R)-3-({[5-bromo-2-(isobutyrylamino)benzoyl]amino}-methyl)piperidine-1-carboxylate 

Relevant articles and documents

One-Pot Synthesis of Some Dynamic 2-Substituted Benzoxazinones and Their Corresponding Qinazolinones of Anticipated Biological Activity

(Chemical Equation Presented) Reactions of 6-bromo-2-isopropyl-4(3H)-3,1-benzoxazin-4-one toward mono- and di-dentate nitrogen nucleophiles, e.g. primary aliphatic and aromatic amines, 1,2-phenylenediamine, hydrazine hydrate, and formamide, have been investigated and afford the corresponding quinazolinones which are expected to have some interesting biological activity. The behavior of 3, 1-benzoxazin-4-one toward active methylene compounds, namely, acetylacetone in basic medium has been studied and gave 3-acetylquinoline. The last reaction is considered as an illustrative model of heterocyclic transformation reactions.

QUINAZOLINONE DERIVATIVES USEFUL FOR THE REGULATION OF GLUCOSE HOMEOSTASIS AND FOOD INTAKE

This invention relates to substituted quinazolinone derivatives, compositions, and methods for treating diabetes, obesity and related disorders, and regulation of food intake (e.g., stimulation and suppression).