76148-76-0Relevant articles and documents
Sulfur-containing derivatives of 1,4-naphthoquinone, part 1: Disulfide synthesis
Stasevych, Maryna V.,Plotnikov, Maxym Yu.,Platonov, Mykola O.,Sabat, Svitlana I.,Musyanovych, Rostyslav Ya.,Novikov, Volodymyr P.
, p. 205 - 211 (2007/10/03)
Bisulfides of 1,4-naphthoquinone were synthesized, and different methods of their synthesis were investigated. High yields and purity of disulfides were obtained from the oxidation of thiol derivatives. The latter were prepared in high yields and purity from isothiuronic salts. The obtained disulfides are synthones for compounds with a wide spectrum of biological activity.
REACTION OF THIOAMIDES WITH 2,3-DICHLORO-1,4-NAPHTHOQUINONE. A NOVEL SYNTHESIS OF NAPHTHOTHIAZOLE-4,9-DIONES
Hammam, A.S.,Bayoumy, B.E.
, p. 71 - 79 (2007/10/02)
The reaction of thioamide II with 2,3-dichloro-1,4-naphthoquinone (I) in ethanol gave naphtho-thiazole-4,9-diones (IV).The intermediates, 2-thioamido-3-chloro-1,4-naphthoquinones III were also isolated from the reaction medium and could be separately transformed to IV by further boiling in aqueous ethanol containing bicarbonate.The reaction of thiosemicarbazide with I under similar conditions gave naphtho-2-amino-4H-1,3,4-thiadiazine-5,10-dione (VII).
