76175-65-0

Basic information

• Product Name: N-benzyl-4,6-dichloropyriMidin-2-aMine
• Synonyms: N-benzyl-4,6-dichloropyriMidin-2-aMine
• CAS NO: 76175-65-0
• Molecular Formula: C₁₁H₉Cl₂N₃
• Molecular Weight: 254.11526
• Mol File: 76175-65-0.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: N-benzyl-4,6-dichloropyriMidin-2-aMine(CAS DataBase Reference)
• NIST Chemistry Reference: N-benzyl-4,6-dichloropyriMidin-2-aMine(76175-65-0)
• EPA Substance Registry System: N-benzyl-4,6-dichloropyriMidin-2-aMine(76175-65-0)

Safety Data

• Hazardous Substances Data: 76175-65-0(Hazardous Substances Data)

Upstream product

• 3764-01-0 2,4,6-trichloropyrimidine 
• 100-46-9 benzylamine 
• 56-05-3 2-Amino-4,6-dichloropyrimidine 
• 100-44-7 benzyl chloride 
• 4489-34-3 4,6-dichloro-2-(methylsulfonyl)pyrimidine 

Downstream Products

• 4214-59-9 2-(benzylamino)pyrimidine 
• 531-08-8 RP 2971 
• 1141923-67-2 3-[4-(2-benzylamino-6-chloro-pyrimidin-4-yloxy)-phenyl]-2-methyl-2-phenoxy-propionic acid ethyl ester 

Relevant articles and documents

Chemoselective reactions of 4,6-dichloro-2-(methylsulfonyl)pyrimidine and related electrophiles with amines

Chemoselective SNAr reactions of 4,6-dichloro-2-(methylsulfonyl) pyrimidine and several related electrophiles with amines and their derivatives are described. In the presence of weak bases anilines and secondary aliphatic amines selectively displace the chloride group. Deprotonated anilines and their carbonyl derivatives displace the sulfone group. Sterically and electronically unbiased primary aliphatic amines selectively displace the sulfone group in 4,6-dichloro-2-(methylsulfonyl)pyrimidine; however, their reactions with other electrophiles generally are less selective. Steric-driven selectivity explanation was proposed. Georg Thieme Verlag Stuttgart. New York.

PYRIMIDINYL-PROPIONIC ACID DERIVATIVES AND THEIR USE AS PPAR AGONISTS

The present invention disclosed compounds of Structural Formula (I), and enantiomer, racemic body, pharmaceutically acceptable salts, solvates or hydrates thereof, wherein variable groups are as defined within, as well as methods for preparing such compou

Benzyl-(2-dimethylaminoethyl)amino]pyrimidine compounds with selective antagonist activity against H1-histamine receptors

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