76186-04-4Relevant articles and documents
Synthesis of new C3 symmetric amino acid- and aminoalcohol-containing chiral stationary phases and application to HPLC enantioseparations
Yu, Jeongjae,Armstrong, Daniel W.,Ryoo, Jae Jeong
, p. 74 - 84 (2017/12/26)
We recently reported a new C3-symmetric (R)-phenylglycinol N-1,3,5-benzenetricarboxylic acid-derived chiral high-performance liquid chromatography (HPLC) stationary phase (CSP 1) that demonstrated better results as compared to a previously described N-3,5-dintrobenzoyl (DNB) (R)-phenylglycinol-derived CSP. Over a decade ago, (S)-leucinol, (R)-phenylglycine, and (S)-leucine derivatives were used as the starting materials of 3,5-DNB-based Pirkle-type CSPs for chiral separation. In this study, three new C3-symmetric CSPs (CSP 2, 3, and 4) were prepared by combining the ideas and results mentioned above. Here we describe the synthetic procedures and applications of the new C3-symmetric CSPs (CSP 2–CSP 4).
Stereoselective synthesis of anti α-methyl-β-methoxy carboxylic compounds
Gálvez, Erik,Romea, Pedro,Urpí, Fèlix,Gondi, Vijaya Bhasker,Rawal, Viresh H.
, p. 81 - 91 (2011/03/21)
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Chelation-Controlled Chemo-, Regio- and Enantio-Selective Synthesis of Homoallylic Alcohols
Calo, Vincenzo,Fiandanese, Vito,Nacci, Angelo,Scilimati, Antonio
, p. 7283 - 7292 (2007/10/02)
Optically active allylic sulphides 10-13, bearing two different leaving groups, react with organocopper reagents by selective substitution of the heterocyclic moiety leading to optically active homoallylic pivalates with chemo-, regio- and enantio-control.This selectivity seems to be related to the coordination exerted by the heterocyclic nucleus towards the organometal.