762-16-3

Basic information

• Product Name: dioctanoyl peroxide
• Synonyms: dioctanoyl peroxide;Caprylyl peroxide.;Dioctanoylperoxid;Dicaprylyl peroxide;Octanoic acid octaneperoxoic anhydride;octanoyl octaneperoxoate;peroxycaprylic acid caprylyl ester
• CAS NO: 762-16-3
• Molecular Formula: C₁₆H₃₀O₄
• Molecular Weight: 286.407
• EINECS: 212-094-2
• Mol File: 762-16-3.mol
• Article Data: 14

Chemical Properties

• Melting Point: 29 °C
• Boiling Point: 348.77°C (rough estimate)
• Flash Point: 149.3°C
• Appearance: /
• Density: 0.9903 (rough estimate)
• Vapor Pressure: 3.57E-05mmHg at 25°C
• Refractive Index: 1.4340 (estimate)
• Water Solubility: 7μg/L at 20℃
• CAS DataBase Reference: dioctanoyl peroxide(CAS DataBase Reference)
• NIST Chemistry Reference: dioctanoyl peroxide(762-16-3)
• EPA Substance Registry System: dioctanoyl peroxide(762-16-3)

Safety Data

• RIDADR: 3106
• HazardClass: 5.2
• PackingGroup: II
• Hazardous Substances Data: 762-16-3(Hazardous Substances Data)

Usage

Uses

Caprylyl Peroxide is used as a catalyst in preparation of poly(vinyl chloride) latexes.

General Description

Straw-colored liquid; sharp odor.

Reactivity Profile

Peroxides, such as dioctanoyl peroxide , are good oxidizing agents. Organic compounds can ignite on contact with concentrated peroxides. Strongly reduced material such as sulfides, nitrides, and hydrides may react explosively with peroxides. There are few chemical classes that do not at least produce heat when mixed with peroxides. Many produce explosions or generate gases (toxic and nontoxic). Generally, dilute solutions of peroxides (<70%) are safe, but the presence of a catalyst (often a transition metal such as cobalt, iron, manganese, nickel, or vanadium) as an impurity may even then cause rapid decomposition, a buildup of heat, and even an explosion. Solutions of peroxides often become explosive when evaporated to dryness or near-dryness. Danger of explosion when dry

Flammability and Explosibility

Notclassified

InChI:InChI=1/C16H30O4/c1-3-5-7-9-11-13-15(17)19-20-16(18)14-12-10-8-6-4-2/h3-14H2,1-2H3

Upstream product

• 111-64-8 n-octanoic acid chloride 
• 124-07-2 Octanoic acid 

Downstream Products

• 408310-94-1 2-heptyl-5-isopentyl-3-methyl-hydroquinone 
• 42036-73-7 1-(non-1-enyl)benzene 
• 67730-31-8 1-phenyl-1-nonanol acetate 
• 67730-32-9 Acetic acid 3-cyano-1-phenyl-undecyl ester 
• 129332-71-4 3-Heptyl-5-methoxy-2-methyl-[1,4]benzoquinone 
• 42036-73-7 1-((E)-non-1-enyl)benzene 
• 111735-48-9 (Z)-1-(non-1-enyl)benzene 
• 6008-36-2 1-phenylnonan-1-one 
• 916728-63-7 1-heptyl-4-phenyl-1H-1,2,3-triazole 

Relevant articles and documents

An improved method for efficient and convenient synthesis of dioctanoyl peroxide

Octanoyl chloride in methylene dichloride was added to the hydrogen peroxide solution containing 5mol.1-1 NaOH in water-cooled flask, the reaction was carried out with high yields in ten or more minutes under vigorous stirring. The product was characterized by elemental analysis, molecular weight and spectral (IR, 1H NMR) analysis. Furthermore, the method proposed has the advantages of operation at room temperature with safety, reliability and short time consuming.

Unnatural α-Amino Acid Synthesized through α-Alkylation of Glycine Derivatives by Diacyl Peroxides

We have developed a protocol for catalyst- and additive-free α-alkylation reactions of glycine derivatives with diacyl peroxides, which proceed by a pathway involving addition of alkyl radicals to imine intermediates. The diacyl peroxide substrate acts as both alkylation agent and oxidizing agent, which means it is atom-economical. It was applied to various glycine derivatives, dipeptides, and a 3,4-dihydroquinoxalin-2(1H)-one derivative and could be carried out on a gram scale, indicating its utility for late-stage functionalization.

Radical alkylation of C(sp3)-H bonds with diacyl peroxides under catalyst-free conditions

Herein, we describe a protocol for alkylation reactions of C(sp3)-H bonds with diacyl peroxides by means of a process involving cross-coupling between an alkyl radical and an α-Aminoalkyl radical. The mild, catalyst-And additive-free conditions make this protocol superior to previously reported C(sp3)-H alkylation strategies. The protocol was applied to 1,2,3,4-Tetrahydroisoquinolines and a tetrahydro-β-carboline derivative and could be carried out on a gram scale, indicating its utility for the alkylation of late-stage synthetic intermediates.