762-68-5

Basic information

• Product Name: 2-Fluoroethanesulfonyl chloride
• Synonyms: 2-Fluoroethanesulfonyl chloride
• CAS NO: 762-68-5
• Molecular Formula: C₂H₄ClFO₂S
• Molecular Weight: 146.57
• Mol File: 762-68-5.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 190.3°C at 760 mmHg
• Flash Point: 68.9°C
• Appearance: /
• Density: 1.474g/cm³
• Vapor Pressure: 0.756mmHg at 25°C
• Refractive Index: 1.418
• CAS DataBase Reference: 2-Fluoroethanesulfonyl chloride(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Fluoroethanesulfonyl chloride(762-68-5)
• EPA Substance Registry System: 2-Fluoroethanesulfonyl chloride(762-68-5)

Safety Data

• Hazardous Substances Data: 762-68-5(Hazardous Substances Data)

Usage

InChI:InChI=1/C2H4ClFO2S/c3-7(5,6)2-1-4/h1-2H2

Upstream product

• 505-13-5 fluoro-2 ethylthiocyanate 
• 162308-79-4 benzyl(2-fluoroethyl)sulfane 
• 7732-18-5 water 
• 7782-50-5 chlorine 
• 462-31-7 thioacetic acid-2-fluoroethyl ester 

Downstream Products

• 677-25-8 ethylenesulfonyl fluoride 
• 460-46-8 2-fluoro-ethanesulfonyl fluoride 
• 1446232-85-4 N-[4-(4-cyanophenoxy)-3-(6-methyl-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridin-4-yl)phenyl]-2-fluoroethanesulfonamide 
• 1446232-63-8 2-fluoro-N-[3-(6-methyl-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridin-4-yl)-4-(tetrahydrofuran-3-yloxy)phenyl]ethanesulfonamide 

Relevant articles and documents

Nitrogen-containing, fluoroalkyl sulfonyl chloride method for the preparation of (by machine translation)

The invention discloses a nitrogen-containing, fluoroalkyl sulfonyl chloride method for preparing, by containing nitrogen/perfluoroalkyl alcohol as the raw material, under the alkaline condition and a sulfonyl chloride the reaction produces the corresponding nitrogen-containing/perfluoroalkyl sulfonate ester, then nitrogen-containing/perfluoroalkyl sulfonate ester with a thio acetic acid potassium generating affinity substitution reaction to produce the nitrogen-containing/Fluoalkyl thiophosphoro acetate, then the chlorine treatment to obtain nitrogen-containing/fluoroalkyl sulfonyl chloride. The synthesis of this invention containing nitrogen (fluoro) alkyl sulfonyl chloride, the compound is a drug, pesticide research and development and production of important pharmaceutical intermediate, the compound of preparation of the alkyl sulfonyl chloride synthesis of pharmaceutical intermediates database, to the market to provide alkyl sulfonyl chloride can be synthetic fragment. Raw materials used in the present invention chemical reagent is commercially available, low cost, short synthetic route, high yield, high product purity chemical, provides high-purity products, so as to obtain higher economic benefits. (by machine translation)