7621-81-0

Basic information

• Product Name: 4-(2-nitrobenzylidene)-2-phenyl-1,3-oxazol-5(4H)-one
• CAS NO: 7621-81-0
• Molecular Formula: C₁₆H₁₀N₂O₄
• Molecular Weight: 294.2616
• Mol File: 7621-81-0.mol
• Article Data: 20

Chemical Properties

• Boiling Point: 464.1°C at 760 mmHg
• Flash Point: 234.5°C
• Density: 1.34g/cm³
• Vapor Pressure: 8.59E-09mmHg at 25°C
• Refractive Index: 1.648
• CAS DataBase Reference: 4-(2-nitrobenzylidene)-2-phenyl-1,3-oxazol-5(4H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(2-nitrobenzylidene)-2-phenyl-1,3-oxazol-5(4H)-one(7621-81-0)
• EPA Substance Registry System: 4-(2-nitrobenzylidene)-2-phenyl-1,3-oxazol-5(4H)-one(7621-81-0)

Safety Data

• Hazardous Substances Data: 7621-81-0(Hazardous Substances Data)

Upstream product

• 495-69-2 Hippuric Acid 
• 552-89-6 2-nitro-benzaldehyde 
• 133721-90-1 sodium hydroxy(2-nitrophenyl)methanesulfonate 
• 532-94-5 sodium hippurate 
• 98-88-4 benzoyl chloride 
• 1199-01-5 2-phenylazlactone 

Downstream Products

• 85115-10-2 3-amino-1,2,3,4-tetrahydroquinolin-2-one 
• 95161-06-1 4-(2-nitro-benzhydryl)-2-phenyl-4H-oxazol-5-one 
• 138973-12-3 1,4-Bis(5'-(2-nitrobenzylidene)-2'-phenyl-4'-imidazolinone-3'-ylamino)phthalazine 
• 109876-82-6 7-(2-Nitro-phenyl)-2,5-diphenyl-oxazolo[5,4-b]pyridine 
• 40108-56-3 α-benzoylamino-2-nitro-cinnamic acid hydrazide 
• 126244-67-5 α-benzoylamino-2-nitro-cinnamic acid benzylidenehydrazide 
• 126293-24-1 5-[1-(2-Nitro-phenyl)-meth-(Z)-ylidene]-2-phenyl-3-{[1-phenyl-meth-(E)-ylidene]-amino}-3,5-dihydro-imidazol-4-one 
• 126293-30-9 3-{[1-(4-Bromo-phenyl)-meth-(E)-ylidene]-amino}-5-[1-(2-nitro-phenyl)-meth-(Z)-ylidene]-2-phenyl-3,5-dihydro-imidazol-4-one 
• 126244-72-2 N-[(Z)-1-[1-(4-Chloro-phenyl)-meth-(E)-ylidene-hydrazinocarbonyl]-2-(2-nitro-phenyl)-vinyl]-benzamide 
• 126813-16-9 N-[(Z)-1-[1-(4-Bromo-phenyl)-meth-(E)-ylidene-hydrazinocarbonyl]-2-(2-nitro-phenyl)-vinyl]-benzamide 
• 126293-26-3 3-{[1-(2-Chloro-phenyl)-meth-(E)-ylidene]-amino}-5-[1-(2-nitro-phenyl)-meth-(Z)-ylidene]-2-phenyl-3,5-dihydro-imidazol-4-one 
• 126293-27-4 3-{[1-(2-Bromo-phenyl)-meth-(E)-ylidene]-amino}-5-[1-(2-nitro-phenyl)-meth-(Z)-ylidene]-2-phenyl-3,5-dihydro-imidazol-4-one 
• 126244-70-0 N-[(Z)-1-[1-(2-Bromo-phenyl)-meth-(E)-ylidene-hydrazinocarbonyl]-2-(2-nitro-phenyl)-vinyl]-benzamide 

Relevant articles and documents

Design, Synthesis, and Antimicrobial Activity of Novel Fluorine-Containing Imidazolones

Abstract: A simple synthetic protocol have been developed for the preparation of novelN-(4-benzylidene-5-oxo-2-phenyl-4,5-dihydro-1H-imidazol-1-yl)-N′-phenylthiourea derivatives by the reaction of4-benzylidene-2-phenyl-4,5-dihydro-1,3-oxazol-5-ones with N

Silica-supported Solvent Approaches More Facile than the Conventional for Erlenmeyer Synthesis with Our Pyridinium Salts

The synthesis of pyridinium salts by both conventional/silica-supported muffle furnace and microwave approaches is described. We have optimized the Erlenmeyer synthesis of azalactone with various concentrations of our synthesized pyridinium salts. Among t

Greener approach: Ionic liquid [Et3NH][HSO4]-catalyzed multicomponent synthesis of 4-arylidene-2-phenyl-5(4H)oxazolones under solvent-free condition

We have developed simple, greener, safer multicomponent synthesis series of 4-arylidene-2-phenyl-5(4H) oxazolones 4(a-r) catalyzed by Bronsted acid ionic liquid as triethylammonium hydrogen sulfate [Et3NH][HSO4] and catalytic amount of acetic anhydride and sodium acetate with excellent yields (90–99%). The protocol offers economical, environmentally benign, solvent-free conditions, and recycle–reuse of the catalyst and easily available starting as benzoyl chloride 1, amino acid 2 and a variety of aldehydes 3. The cyclization followed by condensation of benzoyl chloride, amino acid, and a variety of aldehydes catalyzed by ILs [Et3NH][HSO4] and catalytic amount of acetic anhydride and sodium acetate. The final products were confirmed by their characterization data such as FTIR, 1H-NMR, 13C-NMR, Mass, high-resolution mass spectra and were compared with its reported method.