7621-89-8

Basic information

• Product Name: 3-(3-methoxyphenyl)prop-2-ynoic acid
• Synonyms: 2-propynoic acid, 3-(3-methoxyphenyl)-
• CAS NO: 7621-89-8
• Molecular Formula: C₁₀H₈O₃
• Molecular Weight: 176.1687
• Mol File: 7621-89-8.mol
• Article Data: 12

Chemical Properties

• Boiling Point: 352°C at 760 mmHg
• Flash Point: 144.3°C
• Density: 1.26g/cm³
• Vapor Pressure: 1.46E-05mmHg at 25°C
• Refractive Index: 1.582
• CAS DataBase Reference: 3-(3-methoxyphenyl)prop-2-ynoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(3-methoxyphenyl)prop-2-ynoic acid(7621-89-8)
• EPA Substance Registry System: 3-(3-methoxyphenyl)prop-2-ynoic acid(7621-89-8)

Safety Data

• Hazardous Substances Data: 7621-89-8(Hazardous Substances Data)

Upstream product

• 6099-04-3 trans-3-methoxycinnamic acid 
• 60583-13-3 α-bromo-3-methoxy-trans-cinnamic acid 
• 98332-36-6 methyl 3-(3-methoxyphenyl)-3-oxo-2-(triphenylphosphoranylidene)propanoate 
• 1711-05-3 m-anisoyl chloride 
• 766-85-8 3-methoxy-1-iodobenzene 
• 471-25-0 Propiolic acid 
• 124-38-9 carbon dioxide 
• 768-70-7 1-ethynyl-3-methoxybenzene 
• 253684-23-0 1,1-dibromo-2-(3-methoxyphenyl)ethene 
• 7515-24-4 (3-methoxyphenyl)propynoic acid methyl ester 

Downstream Products

• 768-70-7 1-ethynyl-3-methoxybenzene 
• 872796-16-2 8-methoxy-1-(3-methoxy-phenyl)-naphthalene-2,3-dicarboxylic acid-anhydride 
• 7515-24-4 (3-methoxyphenyl)propynoic acid methyl ester 
• 406687-62-5 {[3-(3-methoxy-phenyl)-propynoyl]-methyl-amino}-acetic acid ethyl ester 
• 849150-03-4 3-(3-methoxy-phenyl)-1-methyl-5-oxo-2,5-dihydro-1H-pyrrole-2-carboxylic acid ethyl ester 
• 1192143-22-8 ethyl 4-((3-methoxyphenyl)ethynyl)benzoate 
• 1310329-78-2 ((3-methoxyphenyl)ethynyl)diphenylphosphine oxide 
• 1372715-30-4 methyl 2-(2-(3-methoxyphenyl)ethynyl)-2-phenylpent-4-enoate 
• 1372715-41-7 methyl 2-(4-bromophenyl)-2-(2-(3-methoxyphenyl)ethynyl)pent-4-enoate 
• 1372715-20-2 allyl 3-(3-methoxyphenyl)propiolate 
• 1017579-86-0 4-(3-methoxyphenyl)-1H-[1,2,3]-triazole 
• 1431960-79-0 C₁₈H₂₄N₂O₄ 
• 1439488-18-2 3-(3-methoxyphenyl)-N-(4-oxo-4H-3,1-benzothiazin-2-yl)-propiolamide 

Relevant articles and documents

N-Heterocyclic carbene-nitrogen molybdenum catalysts for utilization of CO2

Three new N-heterocyclic carbene-nitrogen molybdenum complex was synthesized, and its catalytic activity was evaluated in the cycloaddition of epoxides with CO2. The molybdenum complex combined with tetrabutyl ammonium iodide (TBAI) resulted in a catalytic system for efficient conversion of a wide range of terminal and internal epoxides under 80 °C and 5–7 bar pressure for CO2. The cooperative catalysis mechanism between molybdenum complex and TBAI was elucidated, in which molybdenum complex was used as Lewis acid, and TBAI was employed as nucleophilic reagent. In addition, the NHC-Mo catalytic system was also successfully applied for the direct carboxylation of terminal alkynes with CO2.

Oxidant- and additive-free simple synthesis of 1,1,2-triiodostyrenes by one-pot decaroboxylative iodination of propiolic acids

A metal- and oxidant-free facile synthesis of a range of 1,1,2-triiodostryrene derivatives has been developed which utilizes a simple decarboxylative triiodination of propiolic acids using molecular iodine and sodium acetate in a one-pot manner. Electron-

Visible Light-Catalyzed Decarboxylative Alkynylation of Arenediazonium Salts with Alkynyl Carboxylic Acids: Direct Access to Aryl Alkynes by Organic Photoredox Catalysis

A convenient method mediated by photoredox catalysis is developed for the direct construction of aryl alkynes. Readily available aromatic diazonium salts have been utilized as the aryl radical source to couple alkynyl carboxylic acids to feature the decarboxylative arylation. A wide range of substrates are amenable to this protocol with broad functional group tolerance, and diversely-functionalized aryl alkynes could be synthesized under mild, neutral and transition metal-free reaction conditions using visible light irradiation. Alongside synthetic sustainability associated with the photocatalytic and transition metal-free operation, another key point of this method is that the organic dye catalyst acts as an excited-state reductant, thus establishing the quenching cycle for radical addition and decarboxylative elimination. (Figure presented.).