7622-78-8

Basic information

• Product Name: 4H-1-Benzopyran-2-carboxylic acid, 4-oxo-3-phenyl-
• CAS NO: 7622-78-8
• Molecular Formula: C16H10O4
• Molecular Weight: 266.253
• Mol File: 7622-78-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 4H-1-Benzopyran-2-carboxylic acid, 4-oxo-3-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 4H-1-Benzopyran-2-carboxylic acid, 4-oxo-3-phenyl-(7622-78-8)
• EPA Substance Registry System: 4H-1-Benzopyran-2-carboxylic acid, 4-oxo-3-phenyl-(7622-78-8)

Safety Data

• Hazardous Substances Data: 7622-78-8(Hazardous Substances Data)

Upstream product

• 7622-77-7 2-Hydroxy-2-aethoxycarbonyl-2,3-dihydro-isoflavon 
• 574-12-9 isoflavone 
• 124-38-9 carbon dioxide 
• 33470-08-5 ethyl 4-oxo-3-phenyl-4H-chromene-2-carboxylate 

Relevant articles and documents

A Concise Approach to Oxo-Dehydrorotenoid by Direct Lactonization and the Total Syntheses of Stemonone, Rotenonone, 6-Oxo-dehydroelliptone, and 6-Oxo-6a,12a-dehydrodeguelin

An approach to construct the oxo-dehydrorotenoids via direct lactonization of isoflavone-2-carboxylic acids is reported. The present reaction proceeds smoothly with good substrate scope and an operationally simple protocol. The application of this method

β-Deprotonation by Lithium Di-isopropylamide. Vinyl Carbanions from Oxygen Heterocycles in the Synthesis of Carboxylic Acids in the Benzofuran, Flavone, and Coumarin Series and in the Regiospecific Acylation of 2,6-Dimethylchromone

Lithium di-isopropylamide at -70 deg C can remove the α-proton from benzofuran in the absence of activating groups and the β-proton if such groups are present; in flavone and 4-methoxycoumarin β-deprotonation occurs readily and the carbanions are easily carboxylated giving acids not previously accessible, while in 2,6-dimethylchromone β-deprotonation is kinetically favoured allowing 3-acylation to be achieved separately from the conventional acylation at the 2-methyl group.