76224-05-0

Basic information

• Product Name: (S)-2-(5-Dimethylamino-naphthalene-1-sulfonylamino)-3-phenyl-propionic acid 4-(benzyloxycarbonylamino-imino-methyl)-phenyl ester
• CAS NO: 76224-05-0
• Molecular Weight: 650.755
• Mol File: 76224-05-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-2-(5-Dimethylamino-naphthalene-1-sulfonylamino)-3-phenyl-propionic acid 4-(benzyloxycarbonylamino-imino-methyl)-phenyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-2-(5-Dimethylamino-naphthalene-1-sulfonylamino)-3-phenyl-propionic acid 4-(benzyloxycarbonylamino-imino-methyl)-phenyl ester(76224-05-0)
• EPA Substance Registry System: (S)-2-(5-Dimethylamino-naphthalene-1-sulfonylamino)-3-phenyl-propionic acid 4-(benzyloxycarbonylamino-imino-methyl)-phenyl ester(76224-05-0)

Safety Data

• Hazardous Substances Data: 76224-05-0(Hazardous Substances Data)

Upstream product

• 76223-55-7 N,O-bis(benzyloxycarbonyl)-p-amidinophenol 
• 38148-63-9 p-amidinophenol hydrochloride 
• 1104-36-5 dansyl-L-phenylalanine 
• 76223-53-5 N-(benzyloxycarbonyl)-p-amidinophenol 

Relevant articles and documents

INVERSE SUBSTRATES IX. AMIDINOPHENYL ESTERS DERIVED FROM AMINO ACIDS AND PEPTIDES : SYNTHESIS AND PROPERTIES AS TRYPSIN SUBSTRATES

Methods for preparation of p-amidinophenyl esters from amino acid derivatives are described.Blocking of the amidino function with the benzyloxycarbonyl group and its deblocking by catalytic hydrogenation after coupling were satisfactory. p-Amidino-phenyl esters are of special interest because of their susceptibility to the hydrolytic enzyme, trypsin, and some parameters of the hydrolysis of these compounds by tripsin are presented.Keywords - p-amidinophenyl ester; synthetic substrates; ester formation; trypsin; enzyme kinetics; deacylation rate constant