762297-93-8

Basic information

• Product Name: 2-bromo-1,3,5-trifluoro-4-nitrobenzene
• Synonyms: 2-bromo-1,3,5-trifluoro-4-nitrobenzene
• CAS NO: 762297-93-8
• Molecular Formula: C₆HBrF₃NO₂
• Molecular Weight: 255.9768
• Mol File: 762297-93-8.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 248.2°C at 760 mmHg
• Flash Point: 103.9°C
• Density: 1.967g/cm³
• Vapor Pressure: 0.0388mmHg at 25°C
• Refractive Index: 1.534
• CAS DataBase Reference: 2-bromo-1,3,5-trifluoro-4-nitrobenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 2-bromo-1,3,5-trifluoro-4-nitrobenzene(762297-93-8)
• EPA Substance Registry System: 2-bromo-1,3,5-trifluoro-4-nitrobenzene(762297-93-8)

Safety Data

• Hazardous Substances Data: 762297-93-8(Hazardous Substances Data)

Upstream product

• 2367-76-2 2,4,6-trifluorobromobenzene 

Downstream Products

• 762297-95-0 3-bromo-2,4,6-trifluoroaniline 
• 762297-99-4 N-(3-bromo-2,4,6-trifluorophenyl)-2-methylpropanamide 
• 762298-03-3 tert-butyl 4-[2,4,6-trifluoro-3-(isobutyrylamino)phenyl]-3,6-dihydro-1(2H)-pyridine carboxylate 
• 949096-71-3 4-(2,4,6-trifluoro-3-isobutyrylaminophenyl)piperidine-1-carboxylic acid tert-butyl ester 
• 762298-09-9 2-methyl-N-[2,4,6-trifluoro-3-(4-piperidinyl)phenyl]propanamide 
• 949096-75-7 N-(3-{1-[3-(1,3-dioxo-1,3-dihydroisoindol-2-yl)propyl]piperidin-4-yl}-2,4,6-trifluorophenyl)isobutyramide 
• 949096-78-0 N-{3-[1-(3-aminopropyl)piperidin-4-yl]-2,4,6-trifluorophenyl}isobutyramide 
• 1456507-65-5 (S)-3-((1r,4S)-4-((4-bromo-3,5-difluoro-2-nitrophenyl)amino)cyclohexyl)-5,5-dimethyl-4-phenyloxazolidin-2-one 
• 1456507-66-6 (S)-3-((1r,4S)-4-((2-amino-4-bromo-3,5-difluorophenyl)amino)cyclohexyl)-5,5-dimethyl-4-phenyloxazolidin-2-one 
• 1456507-67-7 (S)-3-((1r,4S)-4-(5-bromo-4,6-difluoro-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)cyclohexyl)-5,5-dimethyl-4-phenyloxazolidin-2-one 
• 1456505-65-9 (S)-3-((1r,4S)-4-(4,6-difluoro-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)cyclohexyl)-5,5-dimethyl-4-phenyloxazolidin-2-one 

Relevant articles and documents

PHENOXY-PYRIDYL-PYRIMIDINE COMPOUNDS AND METHODS OF USE

Described herein are phenoxy-pyridyl -pyrimidine compounds with inositol requiring enzyme 1 (IRE1) modulation activity or function having the Formula I structure or stereoisomers, tautomers, or pharmaceutically acceptable salts thereof, and with the substituents and structural features described herein. Also described are pharmaceutical compositions and medicaments that include the Formula I compounds, as well as methods of using such IRE1 modulators, alone and in combination with other therapeutic agents, for treating diseases or conditions that are mediated or dependent upon estrogen receptors.

IMINOTETRAHYDROPYRIMIDINONE DERIVATIVES AS PLASMEPSIN V INHIBITORS

A series of 2-imino-6-methyltetrahydropyrimidin-4(lH)-one derivatives, substituted in the 6-position by a phenyl moiety which in turn is meta-substituted by an optionally substituted unsaturated fused bicyclic ring system containing at least one nitrogen atom, being selective inhibitors of plasmepsin V activity, are beneficial as pharmaceutical agents, especially in the treatment of malaria.

Amino substituted aryloxybenzylpiperidine derivatives

This invention is directed to Amino substituted Aryloxybenzylpiperidine derivatives which are ligands at the MCH1 receptor. The invention provides a pharmaceutical composition comprising a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. This invention also provides a pharmaceutical composition made by admixing a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. This invention further provides a process for making a pharmaceutical composition comprising combining a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. This invention also provides a method of treating a subject suffering from depression and/or anxiety which comprises administering to the subject an amount of a compound of the subject invention. This invention also provides a method of treating a subject suffering from obesity which comprises administering to the subject an amount of a compound of the subject invention.