7625-59-4

Basic information

• Product Name: Glycine, N-L-phenylalanyl-, methyl ester, monohydrochloride
• Synonyms: HCl*Phe-Gly-OMe;L-Phe-GlyMe hydrochloride;L-Phenylalanylglycinmethylesterhydrochlorid;L-phenylalanylglycine methyl ester hydrochloride;hydrochloride;Phe-Gly-OMe Hydrochlorid;((S)-2-Amino-3-phenyl-propionylamino)-acetic acid methyl ester
• CAS NO: 7625-59-4
• Molecular Formula: C12H16N2O3.ClH
• Molecular Weight: 272.72800
• Mol File: 7625-59-4.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: Glycine, N-L-phenylalanyl-, methyl ester, monohydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: Glycine, N-L-phenylalanyl-, methyl ester, monohydrochloride(7625-59-4)
• EPA Substance Registry System: Glycine, N-L-phenylalanyl-, methyl ester, monohydrochloride(7625-59-4)

Safety Data

• Hazardous Substances Data: 7625-59-4(Hazardous Substances Data)

Upstream product

• 7625-57-2 methyl 2-((2S)-2-((tert-butoxycarbonyl)amino)-3-phenylpropanamido)acetate 
• 5184-17-8 N-benzyloxycarbonyl-L-phenylalanylglycine methyl ester 
• 1161-13-3 N-Cbz-L-Phe 
• 67729-36-6 Boc-Phe-O-COO-isoBu 
• 13734-34-4 N-tert-butoxycarbonyl-L-phenylalanine 
• 50903-54-3 N-[(1,1-dimethylethoxy)carbonyl]-L-phenylalanine pentafluorophenyl ester 

Downstream Products

• 1003593-20-1 Boc-Ala-Phe-Gly-OH 
• 114390-34-0 Pro-Phe-Gly-NH₂ 
• 127331-65-1 Z-Pro-Phe-Gly-NH₂ 
• 131696-96-3 Boc-Thr-Glu(OBzl)-Phe-Gly-OMe 
• 131696-98-5 Boc-Thr-Glu-Phe-Gly-NHNH₂ 
• 131696-97-4 Boc-Thr-Glu-Phe-Gly-OMe 
• 103025-52-1 H-Pro-Pro-Phe-Phe-Gly-NH-NH₂*2HCl 
• 103025-50-9 Boc-Pro-Pro-Phe-Phe-Gly-NH-NH₂ 
• 103025-48-5 Boc-Pro-Pro-Phe-Phe-Gly-OMe 
• 101301-81-9 Boc-Gln-Phe-Phe-Gly-OMe 
• 101301-92-2 H-Leu-Met-Gln-Phe-Phe-Gly-NH-NH₂*HCl 
• 101301-85-3 Boc-Leu-Met-Gln-Phe-Phe-Gly-NH-NH₂ 
• 101301-84-2 Boc-Leu-Met-Gln-Phe-Phe-Gly-OMe 
• 101301-88-6 H-Gln-Phe-Phe-Gly-OMe*HCl 

Relevant articles and documents

Gram-Scale Synthesis of a Hexapeptide by Fragment Coupling in a Ball Mill

Synthesis of long peptides is generally considered as a challenge to peptide chemists, in addition to producing significant amounts of toxic waste, such as DMF. Here we show that using solvent-less methods, such as ball milling, enabled the production of

Synthesis and Biological Evaluation of Analogues of Pro-Leu-Gly-NH2 Modified at the Leucyl Residue

A series of analogues of Pro-Leu-Gly-NH2 (PLG) in which the leucine residue has been replaced with the aliphatic amino acids L-isoleucine, L-2-aminohexanoic acid (Ahx), L-2-aminopentanoic acid, and L-2-aminobutanoic acid and the aromatic amino acids L-phenylalanine, L-phenylglycine, L- and D-2-amino-4-phenylbutanoic acid, L-O-methyltyrosine, and L-4-nitrophenylalanine have been synthesized.These analogues were tested for their ability to enhance the binding of the dopamine receptor agonist 2-amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene (ADTN) to striatal dopamine receptors.Two of the abov e analogues, Pro-Ahx-Gly-NH2 (3) and Pro-Phe-Gly-NH2 (6), showed significant activity in this assay system.Pro-Ahx-Gly-NH2 produced a 16percent enhancement of ADTN binding at 0.1 μM, while Pro-Phe-Gly-NH2 enhanced the binding of ADTN by 31percent at a concentration of 1 μM.

Oligopeptides of β-carboline-3-carboxylic acid - Synthesis and benzodiazepine receptor affinity

-