76263-13-3

Basic information

• Product Name: Fluzinamide
• Synonyms: Fluzinamide;3-[3-(Trifluoromethyl)phenoxy]-1-(methylcarbamoyl)azetidine;AHR-8559
• CAS NO: 76263-13-3
• Molecular Formula: C12H13 F3 N2 O2
• Molecular Weight: 274.24
• Mol File: 76263-13-3.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 415.7°C at 760 mmHg
• Flash Point: 205.2°C
• Appearance: /
• Density: 1.337g/cm³
• Vapor Pressure: 4.04E-07mmHg at 25°C
• Refractive Index: 1.511
• PKA: 14.24±0.40(Predicted)
• CAS DataBase Reference: Fluzinamide(CAS DataBase Reference)
• NIST Chemistry Reference: Fluzinamide(76263-13-3)
• EPA Substance Registry System: Fluzinamide(76263-13-3)

Safety Data

• Hazardous Substances Data: 76263-13-3(Hazardous Substances Data)

Usage

Uses

Anticonvulsant.

InChI:InChI=1/C12H13F3N2O2/c1-16-11(18)17-6-10(7-17)19-9-4-2-3-8(5-9)12(13,14)15/h2-5,10H,6-7H2,1H3,(H,16,18)

Upstream product

• 76263-23-5 3-[3-(trifluoromethyl)phenoxy]azetidine 
• 624-83-9 methyl isocyanate 

Relevant articles and documents

Method of treating muscular tension, muscle spasticity and anxiety with 3-aryloxy and 3-arylthioazetidinecarboxamides

A method of treating animals to obtain muscle relaxation and/or to relieve anxiety is disclosed utilizing novel and known 3-aryloxy and 3-arylthioazetidinecarboxamides having the formula: STR1 wherein Z is oxygen or sulfur; B is oxygen or sulfur; Ar is pyridyl or halo substituted pyridyl, phenyl or substituted phenyl; R1 and R2 are hydrogen, loweralkyl, aryl, allyl groups, propargyl, cycloalkyl, loweralkylcycloalkyl, cycloalkylloweralkyl, arylloweralkyl and diloweralkylaminoalkyl, and R1 and R2 when taken together with the adjacent nitrogen atom may form a heterocyclic amine radical; R3 is hydrogen, loweralkyl, aryl or arylloweralkyl, and the geometrical isomers thereof and pharmaceutical salts thereof and hydrates thereof when they are possible.

Method of treating muscular tension, muscle spasticity and anxiety with 3-aryloxy and 3-arylthioazetidinecarboxamides

A method of treating animals to obtain muscle relaxation and/or to relieve anxiety is disclosed utilizing novel and known 3-aryloxy and 3-arylthioazetidinecarbonxamides having the formula: STR1 wherein Z is oxygen or sulfur; B is oxygen or sulfur; Ar is pyridyl or halo substituted pyridyl, phenyl or substituted phenyl; R1 and R2 are hydrogen, loweralkyl, aryl, allyl groups, propargyl, cycloalkyl, loweralkylcycloalkyl, cycloakylloweralkyl, arylloweralkyl and diloweralkylaminoalkyl, and R1 and R2 when taken together with the adjacent nitrogen atom may form a heterocyclic amine radical; R3 is hydrogen, loweralkyl, aryl or arylloweralkyl, and the geometrical isomers thereof and pharmaceutical salts thereof and hydrates thereof when they are possible.