76263-72-4

Basic information

• Product Name: ethyl N-tosyl-β-anilinopropionate
• Synonyms: ethyl N-tosyl-β-anilinopropionate
• CAS NO: 76263-72-4
• Molecular Weight: 347.435
• Mol File: 76263-72-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: ethyl N-tosyl-β-anilinopropionate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl N-tosyl-β-anilinopropionate(76263-72-4)
• EPA Substance Registry System: ethyl N-tosyl-β-anilinopropionate(76263-72-4)

Safety Data

• Hazardous Substances Data: 76263-72-4(Hazardous Substances Data)

Upstream product

• 140-88-5 ethyl acrylate 
• 62-53-3 aniline 
• 62750-11-2 ethyl 3-phenylaminopropionate 
• 98-59-9 p-toluenesulfonyl chloride 

Downstream Products

• 76298-68-5 2-acetyl-3-phenyl-5-tosyl-3,3a,4,5-tetrahydropyrazolo<4,3-c>quinoline 
• 76263-65-5 (E)-3-[1-(phenyl)-methylidene]-1-(toluene-4-sulfonyl)-2,3-dihydro-1H-quinolin-4-one 
• 14278-37-6 1-tosyl-2,3-dihydroquinolin-4(1H)-one 
• 65148-06-3 N-((4-methylphenyl)sulfonyl)-N-phenyl-beta-alanine 

Relevant articles and documents

Studies in Antifertility Agents: Part XXVII - Synthesis of 2-Acetyl-3-aryl-5-tosyl-7/8-H (or methoxy)-3,3a,4,5-tetrahydropyrazoloquinolines

N-Tosyl-2,3-dihydro-4-quinolones (12-14), prepared from aniline, m- and p-anisidines by reported procedures, on condensation with araldehydes in the presence of NaOMe give the corresponding 3-arylidene-4-quinolones (15-18).Refluxing of 15-18 with NH2-NH2*H2O in gl.AcOH affords the title compounds, 2-acetyl-3-aryl-5-tosyl-7/8-H (or methoxy)-3,3a,4,5-tetrahydropyrazoloquinolines (19-22).The stereochemistry of the title compounds based on the assignments of C3-H, C3a-H, C4-H2 protons has been studied by PMR decoupling experiments.In preliminary screening, compounds 19 and 22 have been found to prevent pregnancy at 20 mg/kg dose in female albino rats, but are ineffective at lower doses.None of the compounds tested shows any significant pharmacological activity.