76277-89-9

Basic information

• Product Name: 2-(tetrafluoro-4-pyridyl)cyclohexanone
• CAS NO: 76277-89-9
• Molecular Weight: 247.192
• Mol File: 76277-89-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-(tetrafluoro-4-pyridyl)cyclohexanone(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(tetrafluoro-4-pyridyl)cyclohexanone(76277-89-9)
• EPA Substance Registry System: 2-(tetrafluoro-4-pyridyl)cyclohexanone(76277-89-9)

Safety Data

• Hazardous Substances Data: 76277-89-9(Hazardous Substances Data)

Upstream product

• 670-80-4 4-cyclohexen-1-ylmorpholine 
• 700-16-3 Pentafluoropyridine 
• 1125-99-1 1-(1-Cyclohexen-1-yl)pyrrolidine 

Relevant articles and documents

Polyhalogenoaromatic Compounds. Part 44. Reactions of Enamines with Polyhalogenopyridines and their N-Oxides

1-Dialkylaminocyclohexenes were readily C-arylated by pentafluoropyridine or 3,5-dichlorotrifluoropyridine but pentachloropyridine was much less reactive.The resulting (tetrahalogenopyridyl)enamines did not cyclise on heating except in the case of compound (10), which gave the heterocycle (16). 1-Dialkylaminocycloalkenes and other enamines were C-arylated by pentachloropyridine N-oxide.In the cases of the dialkylaminocyclo-hexenes and -heptenes the expected pyridylenamines were accompanied by 1-(tetrachloro-2-pyridyl)cyclo-pentene and -hexene, respectively.A mechanism for the ring-contraction leading to the pyridylcycloalkenes is proposed involving a novel elimination of an N-formyldialkylamine.