76278-28-9

Basic information

• Product Name: 4-(3-Bromo-quinolin-2-yl)-2-phenyl-4H-oxazol-5-one
• Synonyms: 4-(3-Bromo-quinolin-2-yl)-2-phenyl-4H-oxazol-5-one
• CAS NO: 76278-28-9
• Molecular Weight: 367.202
• Mol File: 76278-28-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-(3-Bromo-quinolin-2-yl)-2-phenyl-4H-oxazol-5-one(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(3-Bromo-quinolin-2-yl)-2-phenyl-4H-oxazol-5-one(76278-28-9)
• EPA Substance Registry System: 4-(3-Bromo-quinolin-2-yl)-2-phenyl-4H-oxazol-5-one(76278-28-9)

Safety Data

• Hazardous Substances Data: 76278-28-9(Hazardous Substances Data)

Upstream product

• 22615-00-5 3-bromoquinoline N-oxide 
• 1199-01-5 2-phenylazlactone 
• 495-69-2 Hippuric Acid 

Relevant articles and documents

Studies of Tertiary Amine Oxides. LXVIII. (1). Reactions of Aromatic N-Oxides with 2-Substituted 2-Oxazolin-5-ones in the Presence of Acetic Anhydride

Quinoline 1-oxides 1a-f readily react with 2-phenyl- and 2-methyl-2-oxazolin-5-ones, 2a and 2b, in the presence of acetic anhydride to afford 2-substituted 4-(2-quinolyl)-2-oxazolin-5-ones 3a-h in good yields.Hydrolysis of 3a-f with 10percent hydrochloric acid under refluxing conditions gives the corresponding 2-aminomethylquinoline dihydrochlorides 5a-e or monohydrochloride 5f also in good yields.Similar results are obtained from reactions of isoquinoline 2-oxide 9 with 2a,b under the same conditions.