76291-19-5

Basic information

• Product Name: Benzene, 1,2-dimethyl-4-(1-methylpropyl)-
• CAS NO: 76291-19-5
• Molecular Formula: C12H18
• Molecular Weight: 162.275
• Mol File: 76291-19-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Benzene, 1,2-dimethyl-4-(1-methylpropyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1,2-dimethyl-4-(1-methylpropyl)-(76291-19-5)
• EPA Substance Registry System: Benzene, 1,2-dimethyl-4-(1-methylpropyl)-(76291-19-5)

Safety Data

• Hazardous Substances Data: 76291-19-5(Hazardous Substances Data)

Upstream product

• 106-98-9 1-butylene 
• 95-47-6 o-xylene 
• 590-18-1 (Z)-2-Butene 
• 594-11-6 methylcyclopropane 
• 287-23-0 cyclobutane 
• 115-11-7 isobutene 
• 32337-76-1 2-Chloro-4-[1-chloro-meth-(Z)-ylidene]-1-ethyl-1-methyl-3-[1-methyl-prop-(E)-ylidene]-cyclobutane 

Relevant articles and documents

Catalytic protodeboronation of pinacol boronic esters: Formal anti-Markovnikov hydromethylation of alkenes

Pinacol boronic esters are highly valuable building blocks in organic synthesis. In contrast to the many protocols available on the functionalizing deboronation of alkyl boronic esters, protodeboronation is not well developed. Herein we report catalytic protodeboronation of 1°, 2° and 3° alkyl boronic esters utilizing a radical approach. Paired with a Matteson-CH2-homologation, our protocol allows for formal anti-Markovnikov alkene hydromethylation, a valuable but unknown transformation. The hydromethylation sequence was applied to methoxy protected (-)-Δ8-THC and cholesterol. The protodeboronation was further used in the formal total synthesis of δ-(R)-coniceine and indolizidine 209B.

Aromatic Substitution in the Gas Phase. Alkylation of Arenes by C4H9+ Ions from the Protonation of C4 Alkenes and Cycloalkanes with Gaseous Bronsted Acids

Use of a reactive aromatic substrate (o-xylene) to sample the isomeric population of the butyl ions from the gas-phase protonation of the C4H8 hydrocarbons shows that the primary product from linear olefins and methylcyclopropane is the s-butyl ion, or at least an s-butylating charged species displaying a positional selectivity very similar to that measured for the thermal s-butyl cations obtained from n-butane.A fraction of the primary C4H9+ ions isomerizes to the most stable tertiary structure, to an extent which depends, inter alia, on the exothermicity of the proton transfer process.Protonation of cyclobutane gives an alkylating reagent whose s-butylation/t-butylation ratio and positional selectivity set it apart from the C4H9+ reagents obtained from the other C4H8 hydrocarbons, suggesting the intervention of a different electrophile, conceivably protonated cyclobutane.Finally, protonation of isobutene yields exclusively a t-butyl ion that does not isomerize despite the large exothermicity of its formation.