76293-30-6

Basic information

• Product Name: 2-Pyridinamine, N-(1,1-dimethylethyl)-
• CAS NO: 76293-30-6
• Molecular Formula: C9H14N2
• Molecular Weight: 150.224
• Mol File: 76293-30-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-Pyridinamine, N-(1,1-dimethylethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Pyridinamine, N-(1,1-dimethylethyl)-(76293-30-6)
• EPA Substance Registry System: 2-Pyridinamine, N-(1,1-dimethylethyl)-(76293-30-6)

Safety Data

• Hazardous Substances Data: 76293-30-6(Hazardous Substances Data)

Upstream product

• 694-59-7 pyridine N-oxide 
• 75-64-9 tert-butylamine 
• 4124-41-8 p-toluenesulfonylanhydride 

Downstream Products

• 504-29-0 2-aminopyridine 
• 445490-61-9 2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethanol 
• 445490-78-8 tert-butyl 7-(2-hydroxyethyl)-3,4-dihydro-1,8-naphthyridine-1(12H)-carboxylate 
• 243641-37-4 tert-butyl 7-methyl-3,4-dihydro-1,8-naphthyridine-1(2H)-carboxylate 
• 274676-47-0 7-methyl-1,2,3,4-tetrahydro-[1,8]naphthyridine 
• 1569-16-0 2-methyl-[1,8]naphthyridine 
• 7521-41-7 2-Aminonicotinaldehyde 
• 445491-05-4 7-{2-[1-(1-biphenyl-4-yl-2-ethoxycarbonyl-ethyl)-1H-indol-5-yloxy]-ethyl}-3,4-dihydro-2H-[1,8]naphthyridine-1-carboxylic acid tert-butyl ester 
• 445491-22-5 7-(2-{1-[2-ethoxycarbonyl-1-(3-methoxy-phenyl)-ethyl]-1H-indol-5-yloxy}-ethyl)-3,4-dihydro-2H-[1,8]naphthyridine-1-carboxylic acid tert-butyl ester 
• 445491-19-0 7-(2-{1-[2-ethoxycarbonyl-1-(2-methoxy-phenyl)-ethyl]-1H-indol-5-yloxy}-ethyl)-3,4-dihydro-2H-[1,8]naphthyridine-1-carboxylic acid tert-butyl ester 
• 445491-25-8 7-(2-{1-[2-ethoxycarbonyl-1-(4-methoxy-phenyl)-ethyl]-1H-indol-5-yloxy}-ethyl)-3,4-dihydro-2H-[1,8]naphthyridine-1-carboxylic acid tert-butyl ester 
• 445491-31-6 7-(2-{1-[1-(3-Chloro-phenyl)-2-ethoxycarbonyl-ethyl]-1H-indol-5-yloxy}-ethyl)-3,4-dihydro-2H-[1,8]naphthyridine-1-carboxylic acid tert-butyl ester 
• 445490-82-4 7-{2-[1-(2-ethoxycarbonyl-1-phenyl-ethyl)-1H-indol-5-yloxy]-ethyl}-3,4-dihydro-2H-[1,8]naphthyridine-1-carboxylic acid tert-butyl ester 
• 445491-06-5 3-biphenyl-4-yl-3-{5-[2-(5,6,7,8-tetrahydro-[1,8]naphthyridin-2-yl)-ethoxy]-indol-1-yl}-propionic acid ethyl ester 

Relevant articles and documents

A general and efficient 2-amination of pyridines and quinolines

(Chemical Equation Presented) Pyridine N-oxides were converted to 2-aminopyridines in a one-pot fashion using Ts2O-t-BuNH2 followed by in situ deprotection with TFA. The amination proceeded in high yields, excellent 2-/4-selectivity, and with good functional group compatibility. 2-Amino (iso)quinolines were also obtained in the same manner. Combined with the simple oxidation of pyridines to pyridine N-oxides, this method provides a general and efficient way for amination of 2-unsubstituted pyridines.