76306-43-9

Basic information

• Product Name: 3,4-dihydro-6,7-dimethoxy-3-(3,4-dimethoxyphenyl)-1-methylisoquinoline
• Synonyms: 3,4-dihydro-6,7-dimethoxy-3-(3,4-dimethoxyphenyl)-1-methylisoquinoline
• CAS NO: 76306-43-9
• Molecular Weight: 341.407
• Mol File: 76306-43-9.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 3,4-dihydro-6,7-dimethoxy-3-(3,4-dimethoxyphenyl)-1-methylisoquinoline(CAS DataBase Reference)
• NIST Chemistry Reference: 3,4-dihydro-6,7-dimethoxy-3-(3,4-dimethoxyphenyl)-1-methylisoquinoline(76306-43-9)
• EPA Substance Registry System: 3,4-dihydro-6,7-dimethoxy-3-(3,4-dimethoxyphenyl)-1-methylisoquinoline(76306-43-9)

Safety Data

• Hazardous Substances Data: 76306-43-9(Hazardous Substances Data)

Upstream product

• 5471-40-9 3,4,3',4'-tetramethoxy-bibenzyl-α-ylamine 
• 64-19-7 acetic acid 
• 135365-12-7 5-(3,4-Dimethoxy-phenyl)-8,9-dimethoxy-10b-methyl-6,10b-dihydro-5H-oxazolo[2,3-a]isoquinoline-2,3-dione 
• 91486-63-4 1-Methyl-3-(3,4-dimethoxyphenyl)-6,7-dimethoxytetrahydroisoquinoline 
• 76306-62-2 N-<1,2-bis(3,4-dimethoxyphenyl)ethyl>acetamide 
• 4927-55-3 1,2-bis(3,4-dimethoxyphenyl)ethanone 
• 76306-70-2 N-<1,2-bis(3,4-dimethoxyphenyl)ethyl>formamide 

Relevant articles and documents

Synthesis of isoquinolines from 2-phenylethylamines, amides, nitriles and carboxylic acids in polyphosphoric acid

A convenient one pot synthesis of 1-, 1.3-substituted 3,4-dihydroisoquinolines 5 enamines 10 and 3-oxo-2,3-dihydroisoquinolines 18 as well as of enamides 22 of isoquinoline from 2-phenyl-, 1,2-diphenylethylamines, phenylacetamides, phenylacetonitriles, N-acylphenylethylamines and carboxylic acids in nonaqueous media has been accomplished.

Dehydrogenation Reactions of 1-Substituted-3-Aryltetrahydroisoquinoline Derivatives

The 1-substituted-3-aryltetrahydroisoquinolines I have been converted into the corresponding 3,4-dihydro- or isoquinoline derivatives by treatment with several oxidizing agents: iodine in ethanol, palladium on carbon, DDQ and Fremy's salt.The oxidation re