76334-30-0Relevant articles and documents
Processes and intermediates for preparing fulvestrant
-
Paragraph 0040-0043; 0048-0051, (2020/05/30)
The present invention provides a method and an intermediate for preparing fulvestrant, and relates to a method for preparing fulvestrant, and an intermediate (5) of fulvestrant, and a synthetic methodthereof. The method provided by the invention can be used for obtaining high-purity fulvestrant, and is suitable for industrial mass production.
Synthesis and physical properties of ferrocene derivatives (XXV) liquid crystallinity of 1,3-disubstituted ferrocene derivatives
Nakamura, Naotake,Kagawa, Shinya
experimental part, p. 150 - 159 (2012/01/03)
Liquid crystallinity of 1,3-disubstituted ferrocene derivatives was studied by DSC and polarizing microscope. The name of the derivatives is 1,3-bis[-[4-(4-methoxyphenoxycarbonyl)phenoxy]alkyloxycarbonyl]ferrocene. Nine members from n = 2 to 10 were synthesized (n is carbon number of alkyl chain in the sample). All samples except n = 2 and 4 exhibited monotropic nematic liquid crystalline phase. In addition, smectic X (not yet completely identified) was also observed in n = 8 and 10. Liquid crystalline phase transition phenomena were discussed from a viewpoint of molecular shape. Copyright Taylor & Francis Group, LLC.
A New Synthetic Method of Macrocyclic Lactones from ω-Iodoalkylacrylates
Abe, Motoji,Hayashikoshi, Takaoki,Kurata, Takeo
, p. 1789 - 1792 (2007/10/02)
When the photostimulated cyclization reaction of ω-iodoalkylacrylates was performed in the presence of metal hydride complexes such as sodium cyanoborohydride (NaBH3CN), sodium borohydride (NaBH4) and potassium borohydride (KBH4), the corresponding macrocyclic lactones were produced.The use of NaBH3CN led to the highest yield of lactones.