76343-82-3

Basic information

• Product Name: 7,16-bis<2-(p-tolylsulphonylamino)ethyl>-1,4,10-tetraoxa-7,16-diazacyclo-octadecane
• Synonyms: 7,16-bis<2-(p-tolylsulphonylamino)ethyl>-1,4,10-tetraoxa-7,16-diazacyclo-octadecane
• CAS NO: 76343-82-3
• Molecular Weight: 656.865
• Mol File: 76343-82-3.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 7,16-bis<2-(p-tolylsulphonylamino)ethyl>-1,4,10-tetraoxa-7,16-diazacyclo-octadecane(CAS DataBase Reference)
• NIST Chemistry Reference: 7,16-bis<2-(p-tolylsulphonylamino)ethyl>-1,4,10-tetraoxa-7,16-diazacyclo-octadecane(76343-82-3)
• EPA Substance Registry System: 7,16-bis<2-(p-tolylsulphonylamino)ethyl>-1,4,10-tetraoxa-7,16-diazacyclo-octadecane(76343-82-3)

Safety Data

• Hazardous Substances Data: 76343-82-3(Hazardous Substances Data)

Upstream product

• 3634-89-7 N-(p-toluenesulfonyl)aziridine 
• 23978-55-4 1,4,10,13-tetraoxa-7,16-diazacyclooctadecane 

Downstream Products

• 111306-32-2 4,10-bis(p-tolylsulphonyl)-7,16,19,24,27-pentaoxa-1,4,10,13-tetra-azabicyclo<11.8.8>nonacosane 
• 39678-11-0 13,16-bis(p-tolylsulphonyl)-4,7,21,24-tetraoxa-1,10,13,16-tetra-azabicyclo<8.8.8>hexacosane 
• 121031-83-2 4,7,10-tris-(p-tolylsulphonyl)-16,19,24,27-tetraoxa-1,4,7,10,13-penta-azabicyclo<11.8.8>nonacosane 
• 121031-86-5 4,9-bis(p-tolylsulphonyl)benz-15,18,23,26-tetraoxa-1,4,9,12-tetra-azabicyclo<10.8.8>octacosane 
• 113917-92-3 4,13-bis(p-tolylsulphonyl)-7,10,19,22,27,30-hexaoxa-1,4,13,16-tetra-aza<14.8.8>dotriacontane 
• 121031-88-7 4,11-bis(p-tolylsulphonyl)-6,9-etheno-17,20,25,28-tetraoxa-1,4,11,14-tetra-azabicyclo<12.8.8>triaconta-6,8-diene 

Relevant articles and documents

Macroheterocycles; XXXIX. A Convenient Synthesis of Polyaza-oxa Cryptands

A convenient procedure is proposed for the synthesis of cryptands by the alkylation of bis-N-(2-tosylaminoethyl)diaza-crown ethers with dibromides in the two-phase system: aqueous sodium hydroxide/toluene.

MACROHETEROCYCLES. PART 44. FACILE SYNTHESIS OF AZACROWN ETHERS AND CRYPTANDS IN A TWO-PHASE SYSTEM

A facile procedure is proposed for the preparation of azacrown ethers and cryptands by condensation of dibromides or ethylene glycol bis(toluene-p-sulphonate)s with acyclic bis(sulphonamide)s or with bisdiazacrown ethers, respectively.The reaction was carried out in a two-phase system of aqueous alkali-toluene (benzene)in the presence of quaternary ammonium salts as phase transfer catalysts.The catalytic activity decreased in the sequence: Bu4NI ca.Bu4NBr > Bu4NCl > Bu4NHSO4 > Et3NCH2C6H5NCl.Maximum yields of twelve-membered azacrown ethers are obtained when lithium hydroxide is used, while crown ethers of larger size are observed in the presence of sodium or potassium hydroxides; this may be due to a template effect.