76357-12-5Relevant articles and documents
Structural Reassignment and Absolute Stereochemistry of Madurastatin C1 (MBJ-0034) and the Related Aziridine Siderophores: Madurastatins A1, B1, and MBJ-0035
Tyler, Andrew R.,Mosaei, Hamed,Morton, Stephanie,Waddell, Paul G.,Wills, Corinne,McFarlane, William,Gray, Joe,Goodfellow, Michael,Errington, Jeff,Allenby, Nick,Zenkin, Nikolay,Hall, Michael J.
supporting information, p. 1558 - 1562 (2017/05/31)
The madurastatins are pentapeptide siderophores originally described as containing an unusual salicylate-capped N-terminal aziridine ring. Isolation of madurastatin C1 (1) (also designated MBJ-0034), from Actinomadura sp. DEM31376 (itself isolated from a
Straightforward synthesis and antioxidant studies of chalcogenoaziridines
Borges, Rodrigo,Andrade, Floyd C.D.,Schwab, Ricardo S.,Sousa, Fernanda S.S.,de Souza, Maurice Neto,Savegnago, Lucielli,Schneider, Paulo H.
supporting information, p. 3501 - 3504 (2016/07/15)
Herein we reported the synthesis of chalcogenoaziridines through the introduction of the organoselenium moiety in the aziridine framework through the nucleophilic substitution of the OTs leaving group. In addition, the antioxidant activity, as reflected b
Structure-activity relationship (SAR) of the α-amino acid residue of potent tetrahydroisoquinoline (THIQ)-derived LFA-1/ICAM-1 antagonists
Zhong, Min,Hanan, Emily J.,Shen, Wang,Bui, Minna,Arkin, Michelle R.,Barr, Kenneth J.,Evanchik, Marc J.,Hoch, Ute,Hyde, Jennifer,Martell, Jose R.,Oslob, Johan D.,Paulvannan, Kumar,Prabhu, Saileta,Silverman, Jeffrey A.,Wright, Jasmin,Yu, Chul H.,Zhu, Jiang,Flanagan, W. Mike
scheme or table, p. 307 - 310 (2011/02/27)
This letter describes the structure-activity relationship (SAR) of the 'right-wing' α-amino acid residue of potent tetrahydroisoquinoline (THIQ)-derived LFA-1/ICAM-1 antagonists. Novel (S)-substituted heteroaryl-bearing α-amino acids have been identified