76387-90-1

Basic information

• Product Name: 4-(p-chlorophenyl)-6-methyl-1-phenyl-2(1H)-pyrimidinone
• Synonyms: 4-(p-chlorophenyl)-6-methyl-1-phenyl-2(1H)-pyrimidinone
• CAS NO: 76387-90-1
• Molecular Weight: 296.756
• Mol File: 76387-90-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-(p-chlorophenyl)-6-methyl-1-phenyl-2(1H)-pyrimidinone(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(p-chlorophenyl)-6-methyl-1-phenyl-2(1H)-pyrimidinone(76387-90-1)
• EPA Substance Registry System: 4-(p-chlorophenyl)-6-methyl-1-phenyl-2(1H)-pyrimidinone(76387-90-1)

Safety Data

• Hazardous Substances Data: 76387-90-1(Hazardous Substances Data)

Upstream product

• 64-10-8 phenyl carbamate 
• 6302-55-2 1-(4'-chlorophenyl)-1,3-butanedione 

Downstream Products

• 4211-87-4 3-methyl-5-(p-chlorophenyl)isoxazole 

Relevant articles and documents

The Selective Preparation of 1,4-Diaryl-6-methyl- and 1,6-Diaryl-4-methyl-2-(1H)pyrimidinones

N-Phenylurea reacted with benzoylacetone derivatives (I) to give 1,4-diaryl-6-methyl-2-(1H)pyrimidinones (II) in addition to low yields of 1,6-diaryl-4-methyl-2-(1H)pyrimidinones (IV), while N-phenylthiourea afforded only 1,6-diaryl-4-methyl-2-(1H)pyrimidinethiones (III) in good yields.Further 1,6-diaryl-4-methyl-2-(1H)pyrimidinethiones (III) were succesfully converted in satisfactory yields into the corresponding 2-(1H)pyrimidinones (IV) by the treatment with methyl iodide in the presence of sodium methoxide in methanol at room temperature.