76397-85-8 Usage
Classification
Flavonoids
A family of plant-derived compounds with various biological activities
Properties
Antioxidant and anti-inflammatory
Sources
Fruits, vegetables, and herbal remedies
Commonly found in various plant-based foods and used in traditional medicine for their potential health benefits
Chemical structure
Benzopyran ring with a 4H-1-benzopyran-4-one core
A specific arrangement of atoms that forms the basis of the compound's properties and activities
Functional groups
Hydroxyl and methoxy groups attached to the phenyl ring
These groups influence the compound's reactivity, solubility, and interaction with other molecules
Research focus
Potential health benefits and treatment/prevention of diseases and conditions
The compound has been studied for its possible positive effects on human health and its role in addressing various medical issues
Check Digit Verification of cas no
The CAS Registry Mumber 76397-85-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,6,3,9 and 7 respectively; the second part has 2 digits, 8 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 76397-85:
(7*7)+(6*6)+(5*3)+(4*9)+(3*7)+(2*8)+(1*5)=178
178 % 10 = 8
So 76397-85-8 is a valid CAS Registry Number.
InChI:InChI=1/C16H14O5/c1-20-10-4-2-9(3-5-10)12-8-21-15-7-14(18)13(17)6-11(15)16(12)19/h2-7,12,17-18H,8H2,1H3
76397-85-8Relevant articles and documents
Structure-activity relationship studies of flavonoids as potent inhibitors of human platelet 12-hLO, reticulocyte 15-hLO-1, and prostate epithelial 15-hLO-2
Vasquez-Martinez, Yesseny,Ohri, Rachana V.,Kenyon, Victor,Holman, Theodore R.,Sepulveda-Boza, Silvia
, p. 7408 - 7425 (2008/09/18)
Human lipoxygenase (hLO) isozymes have been implicated in a number of disease states and have attracted much attention with respect to their inhibition. One class of inhibitors, the flavonoids, have been shown to be potent lipoxygenase inhibitors but their study has been restricted to those compounds found in nature, which have limited structural variability. We have therefore carried out a comprehensive study to determine the structural requirements for flavonoid potency and selectivity against platelet 12-hLO, reticulocyte 15-hLO-1, and prostate epithelial 15-hLO-2. We conclude from this study that catechols are essential for high potency, that isoflavones and isoflavanones tend to select against 12-hLO, that isoflavans tend to select against 15-hLO-1, but few flavonoids target 15-hLO-2.
