76397-87-0 Usage
General Description
3,4-dihydro-3-(4-methoxyphenyl)-2H-1-benzopyran-6,7-diol, also known as 3,4-dihydroxy-6,7-dimethoxy-2-phenylchroman, is a chemical compound with potential antioxidant, anti-inflammatory, and neuroprotective properties. It is a flavonoid derivative that is found in certain plants and has been studied for its potential therapeutic effects. Research suggests that this compound may have protective effects against oxidative stress and inflammation, making it a potential candidate for the development of new drugs for the treatment of various conditions. Its chemical structure and properties make it an interesting target for further investigation in pharmacological and medicinal research.
Check Digit Verification of cas no
The CAS Registry Mumber 76397-87-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,6,3,9 and 7 respectively; the second part has 2 digits, 8 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 76397-87:
(7*7)+(6*6)+(5*3)+(4*9)+(3*7)+(2*8)+(1*7)=180
180 % 10 = 0
So 76397-87-0 is a valid CAS Registry Number.
InChI:InChI=1/C16H16O4/c1-19-13-4-2-10(3-5-13)12-6-11-7-14(17)15(18)8-16(11)20-9-12/h2-5,7-8,12,17-18H,6,9H2,1H3
76397-87-0Relevant articles and documents
Structure-activity relationship studies of flavonoids as potent inhibitors of human platelet 12-hLO, reticulocyte 15-hLO-1, and prostate epithelial 15-hLO-2
Vasquez-Martinez, Yesseny,Ohri, Rachana V.,Kenyon, Victor,Holman, Theodore R.,Sepulveda-Boza, Silvia
, p. 7408 - 7425 (2008/09/18)
Human lipoxygenase (hLO) isozymes have been implicated in a number of disease states and have attracted much attention with respect to their inhibition. One class of inhibitors, the flavonoids, have been shown to be potent lipoxygenase inhibitors but their study has been restricted to those compounds found in nature, which have limited structural variability. We have therefore carried out a comprehensive study to determine the structural requirements for flavonoid potency and selectivity against platelet 12-hLO, reticulocyte 15-hLO-1, and prostate epithelial 15-hLO-2. We conclude from this study that catechols are essential for high potency, that isoflavones and isoflavanones tend to select against 12-hLO, that isoflavans tend to select against 15-hLO-1, but few flavonoids target 15-hLO-2.
