76399-19-4

Basic information

• Product Name: (E)-3-bromo-5,5-dimethyl-2-cyclohexenylidene acetonitrile
• CAS NO: 76399-19-4
• Molecular Weight: 226.116
• Mol File: 76399-19-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (E)-3-bromo-5,5-dimethyl-2-cyclohexenylidene acetonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-3-bromo-5,5-dimethyl-2-cyclohexenylidene acetonitrile(76399-19-4)
• EPA Substance Registry System: (E)-3-bromo-5,5-dimethyl-2-cyclohexenylidene acetonitrile(76399-19-4)

Safety Data

• Hazardous Substances Data: 76399-19-4(Hazardous Substances Data)

Upstream product

• 2537-48-6 diethyl 1-cyanomethylphosphonate 
• 13271-49-3 3-bromo-5,5-dimethlycyclohex-2-en-1-one 

Relevant articles and documents

Reaction de wittig-horner entre phosphonates et cyclohexenones β-substituees

Various procedures were attempted in order to prepare α,β,γ,δ-unsaturated nitriles via the Wittig-Horner reaction of β-substituted cyclohex-2-en-1-ones with diethyl cyanomethyl phosphonate. Among them, the one using NaH as base in refluxing THF gives only the products resulting from carbonyl attack, in good yields. The stereochemistry of the reaction is discussed.