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76420-75-2

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76420-75-2 Usage

Description

(S)-1-[N-[1-(ethoxycarbonyl)-3-phenylpropyl]-L-alanyl]-L-proline maleate is a chemical compound that serves as an active pharmaceutical ingredient, specifically belonging to the class of ACE inhibitors. It is designed to lower blood pressure and treat heart failure by blocking the production of substances that constrict blood vessels. (S)-1-[N-[1-(ethoxycarbonyl)-3-phenylpropyl]-L-alanyl]-L-proline maleate is presented in a salt form, which is a combination of (S)-1-[N-[1-(ethoxycarbonyl)-3-phenylpropyl]-L-alanyl]-L-proline and maleic acid. The maleate salt form enhances the stability and solubility of the active ingredient in water, facilitating its formulation into pharmaceutical dosage forms such as tablets or capsules. As a therapeutic agent, (S)-1-[N-[1-(ethoxycarbonyl)-3-phenylpropyl]-L-alanyl]-L-proline maleate offers significant benefits for patients with cardiovascular conditions.

Uses

Used in Pharmaceutical Industry:
(S)-1-[N-[1-(ethoxycarbonyl)-3-phenylpropyl]-L-alanyl]-L-proline maleate is used as an active pharmaceutical ingredient for the treatment of high blood pressure and heart failure. It functions by inhibiting the production of substances that cause blood vessel constriction, thereby reducing blood pressure and improving heart function.
Used in Cardiovascular Applications:
In the field of cardiology, (S)-1-[N-[1-(ethoxycarbonyl)-3-phenylpropyl]-L-alanyl]-L-proline maleate is utilized as a therapeutic agent to manage cardiovascular conditions. Its role as an ACE inhibitor helps in the regulation of blood pressure and provides relief from the symptoms of heart failure, making it a valuable component in the treatment of various heart-related ailments.
Used in Drug Formulation:
The maleate salt form of (S)-1-[N-[1-(ethoxycarbonyl)-3-phenylpropyl]-L-alanyl]-L-proline enhances the stability and solubility of the compound in water. This characteristic is crucial in the drug formulation process, as it allows for the creation of pharmaceutical dosage forms such as tablets or capsules, which are essential for patient compliance and effective drug delivery.

Check Digit Verification of cas no

The CAS Registry Mumber 76420-75-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,6,4,2 and 0 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 76420-75:
(7*7)+(6*6)+(5*4)+(4*2)+(3*0)+(2*7)+(1*5)=132
132 % 10 = 2
So 76420-75-2 is a valid CAS Registry Number.

76420-75-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name (S)-1-[N-[1-(ethoxycarbonyl)-3-phenylpropyl]-L-alanyl]-L-proline maleate

1.2 Other means of identification

Product number -
Other names Enacyloxin iia

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:76420-75-2 SDS

76420-75-2Downstream Products

76420-75-2Relevant articles and documents

Reductive amination of ethyl 2-oxo-4-phenylbutanoate with L-alanyl-L-proline. Synthesis of enalapril maleate

Wyvratt,Tristram,Ikeler,et al.

, p. 2816 - 2819 (2007/10/02)

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