76429-69-1

Basic information

• Product Name: 5-chloro-2,3-dihydro-1-benzofuran
• Synonyms: 5-chloro-2,3-dihydro-1-benzofuran;5-Chloro-2,3-dihydrobenzofuran
• CAS NO: 76429-69-1
• Molecular Formula: C₈H₇ClO
• Molecular Weight: 154.59358
• EINECS: -0
• Mol File: 76429-69-1.mol
• Article Data: 13

Chemical Properties

• Appearance: /
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility: Chloroform (Slightly), Methanol (Slightly)
• CAS DataBase Reference: 5-chloro-2,3-dihydro-1-benzofuran(CAS DataBase Reference)
• NIST Chemistry Reference: 5-chloro-2,3-dihydro-1-benzofuran(76429-69-1)
• EPA Substance Registry System: 5-chloro-2,3-dihydro-1-benzofuran(76429-69-1)

Safety Data

• Hazardous Substances Data: 76429-69-1(Hazardous Substances Data)

Usage

Description

5-chloro-2,3-dihydro-1-benzofuran is a chlorinated derivative of 2,3-dihydro-1-benzofuran, a heterocyclic compound with a benzene ring fused to a furan ring. Its molecular formula is C8H7ClO, and the presence of the chlorine atom imparts unique chemical and physical properties to the compound.

Uses

Used in Chemical Synthesis:
5-chloro-2,3-dihydro-1-benzofuran is used as a building block in the synthesis of other organic compounds, particularly in the production of fine chemicals. Its structure and reactivity make it a valuable tool for chemical research and development.
Used in Pharmaceutical Industry:
5-chloro-2,3-dihydro-1-benzofuran may have potential uses in the pharmaceutical industry, although further research is needed to explore its specific applications in this field. Its unique chemical properties could potentially be harnessed for the development of new drugs or drug delivery systems.

Upstream product

• 76429-65-7 1-(2-bromoethoxy)-2-bromo-4-chlorobenzene 
• 121767-82-6 2-Bromo-4-chloro-1-(2-chloro-ethoxy)-benzene 
• 115997-75-6 6-Chloro-1a,7b-dihydro-2H-1,3-dioxa-cyclopropa[a]naphthalene 
• 496-16-2 2.3-dihydrobenzofuran 
• 695-96-5 2-bromo-4-chlorophenol 
• 23145-05-3 5-chlorobenzofuran 

Relevant articles and documents

Efficient halogenation synthesis method of aryl halide

The invention discloses an efficient halogenation synthesis method of aryl halide. The method comprises the following step: in the presence of a catalyst (sulfoxide or oxynitride), a halogenation reagent and a solvent, carrying out a halogenation reaction on an aromatic ring compound to obtain the aryl halide. According to the present invention, in the presence of a catalyst (sulfoxide or nitrogenoxide), a halogenation reagent and a solvent, the aromatic ring is subjected to an efficient halogenation reaction, such that the very useful aryl halide can be obtained with high activity and high selectivity; and by adopting the method disclosed by the invention, aryl halides can be efficiently synthesized, and the method has a wide application prospect in actual production.

HETEROCYCLIC COMPOUND

Provided is a heterocyclic compound that may have a GCN2 inhibitory action, and is expected to be useful for the prophylaxis or treatment of GCN2 associated diseases including cancer and the like. A compound represented by the formula (I): wherein each symbol is as described in the DESCRIPTION, or a salt thereof.

Copper-Catalyzed Reductive Cross-Coupling of Nonactivated Alkyl Tosylates and Mesylates with Alkyl and Aryl Bromides

A copper-catalyzed reductive cross-coupling reaction of nonactivated alkyl tosylates and mesylates with alkyl and aryl bromides was developed. It provides a practical method for efficient and cost-effective construction of aryl-alkyl and alkyl-alkyl C=C bonds with stereocontrol from readily available substrates. When used in an intramolecular fashion, the reaction enables convenient access to various substituted carbo- or heterocycles, such as 2,3-dihydrobenzofuran and benzochromene derivatives.