76475-63-3

Basic information

• Product Name: 4-[(2,4-DIMETHYLPHENYL)AMINO]-4-OXOBUTANOIC ACID
• Synonyms: N-(2,4-DIMETHYL-PHENYL)-SUCCINAMIC ACID;IFLAB-BB F0358-0042;4-[(2,4-DIMETHYLPHENYL)AMINO]-4-OXOBUTANOIC ACID;3-[(2,4-DIMETHYLPHENYL)CARBAMOYL]PROPANOIC ACID;2',4'-DIMETHYLSUCCINANILIC ACID
• CAS NO: 76475-63-3
• Molecular Formula: C₁₂H₁₅NO₃
• Molecular Weight: 221.25
• Mol File: 76475-63-3.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-[(2,4-DIMETHYLPHENYL)AMINO]-4-OXOBUTANOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 4-[(2,4-DIMETHYLPHENYL)AMINO]-4-OXOBUTANOIC ACID(76475-63-3)
• EPA Substance Registry System: 4-[(2,4-DIMETHYLPHENYL)AMINO]-4-OXOBUTANOIC ACID(76475-63-3)

Safety Data

• Hazardous Substances Data: 76475-63-3(Hazardous Substances Data)

Upstream product

• 108-30-5 succinic acid anhydride 
• 95-68-1 2,4-Xylidine 

Downstream Products

• 1811-85-4 3-(2,4-dimethylphenyl)propionic acid 
• 306325-28-0 N-(2,4-dimethyl-phenyl)-succinamic acid methyl ester 

Relevant articles and documents

Chemoselective acylation of amines in aqueous media

Amines are efficiently acylated by both cyclic and acyclic anhydrides by dissolving them in an aqueous medium with the help of a surfactant, sodium dodecyl sulfate (SDS). Cyclic and acyclic anhydrides react with equal ease with an amine, and amines with various stereo-electronic factors react at the same rates with an anhydride. Chemoselective acylation of amines in the presence of phenols and thiols and of thiols in the presence of phenols has been achieved. No acidic or basic reagents are used during the reaction. No Chromatographic separation is required for isolation of the acylated products. Reactions in a neutral aqueous medium, easy isolation of products, and innocuous by-products make the present method a green chemical process. Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004.