76488-08-9

Basic information

• Product Name: 7-chloro-5-(2-fluorophenyl)-N-methoxy-alpha-nitro-3H-1,4-benzodiazepine-2-methanimine
• Synonyms: 7-chloro-5-(2-fluorophenyl)-N-methoxy-alpha-nitro-3H-1,4-benzodiazepine-2-methanimine
• CAS NO: 76488-08-9
• Molecular Weight: 374.759
• Mol File: 76488-08-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 7-chloro-5-(2-fluorophenyl)-N-methoxy-alpha-nitro-3H-1,4-benzodiazepine-2-methanimine(CAS DataBase Reference)
• NIST Chemistry Reference: 7-chloro-5-(2-fluorophenyl)-N-methoxy-alpha-nitro-3H-1,4-benzodiazepine-2-methanimine(76488-08-9)
• EPA Substance Registry System: 7-chloro-5-(2-fluorophenyl)-N-methoxy-alpha-nitro-3H-1,4-benzodiazepine-2-methanimine(76488-08-9)

Safety Data

• Hazardous Substances Data: 76488-08-9(Hazardous Substances Data)

Upstream product

• 109-99-9 tetrahydrofuran 
• 186581-53-3 diazomethane 
• 76488-35-2 7-chloro-5-(2-fluorophenyl)-N-hydroxy-alpha-nitro-3H-1,4-benzodiazepine-2-methanimine 
• 59467-63-9 7-chloro-5-(2-fluorophenyl)-2-nitromethylene-1,3-dihydro-2H-1,4-benzodiazepine 

Downstream Products

• 2886-65-9 7-chloro-5-(2-fluorophenyl)-1,3-dihydro-1,4-benzodiazepin-2(2H)-one 
• 76488-20-5 7-chloro-5-(2-fluorophenyl)-N'-methoxy-3H-1,4-benzodiazepine-2-carboximidamide 
• 87120-54-5 7-chloro-5-(2-fluorophenyl)-N-methoxy-3H-1,4-benzodiazepine-2-carboximidic acid methyl ester 

Relevant articles and documents

Quinazolines and 1,4-benzodiazepines. XCIII. (1). Synthesis of imidazo[1,5-a][1,4]benzodiazepines from nitrooximes

The displacement of the nitro group in nitrooximes by other nucleophiles was used to prepare various 2-(hydroxyimino)methyl- and 2-(methoxyimino)methyl-1,4-benzodiazepines. These compounds were converted to imidazo[1,5-α][1,4]benzodiazepines bearing a tertiary amine, methoxy or thiomethyl group in the 3-position.