7650-89-7 Usage
Description
TRIBENZYLPHOSPHINE is an organophosphine compound that serves as a versatile co-catalyst in various chemical reactions. It is known for its ability to enhance the efficiency and selectivity of catalytic processes, making it a valuable component in the synthesis of a wide range of compounds.
Uses
Used in Pharmaceutical Industry:
TRIBENZYLPHOSPHINE is used as a co-catalyst for the preparation of coumarin derivatives via nickel-catalyzed cycloaddition. This application is significant in the synthesis of pharmaceutical compounds, as coumarin derivatives possess a wide range of biological activities, including anticoagulant, anti-inflammatory, and antithrombotic properties.
Used in Polymer Industry:
TRIBENZYLPHOSPHINE is utilized as a co-catalyst in copolymerization reactions, which are essential for the production of various polymers with specific properties. These polymers find applications in a multitude of industries, including automotive, electronics, and packaging.
Used in Chemical Synthesis:
TRIBENZYLPHOSPHINE is employed as a co-catalyst in Rh-catalyzed hydroformylation reactions, which are crucial for the production of aldehydes. These aldehydes serve as key intermediates in the synthesis of various chemicals, pharmaceuticals, and agrochemicals.
Used in Platinum-Catalyzed Oxidative Hydroxylation:
TRIBENZYLPHOSPHINE is used as a co-catalyst in platinum-catalyzed oxidative hydroxylation reactions, which are vital for the synthesis of various organic compounds, including those with potential applications in the pharmaceutical and agrochemical industries.
Used in Ruthenium-Catalyzed Metathesis Reactions:
TRIBENZYLPHOSPHINE is utilized as a co-catalyst in ruthenium-catalyzed metathesis reactions, which are essential for the synthesis of complex organic molecules, such as natural products and pharmaceutical compounds.
Used in the Preparation of Substituted Allylamines:
TRIBENZYLPHOSPHINE is used as a co-catalyst in the preparation of substituted allylamines by three-component coupling of alkynes, imines, and organoboranes. This method is significant for the synthesis of various organic compounds with potential applications in the pharmaceutical and agrochemical industries.
Check Digit Verification of cas no
The CAS Registry Mumber 7650-89-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,6,5 and 0 respectively; the second part has 2 digits, 8 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 7650-89:
(6*7)+(5*6)+(4*5)+(3*0)+(2*8)+(1*9)=117
117 % 10 = 7
So 7650-89-7 is a valid CAS Registry Number.
InChI:InChI=1/C21H21P/c1-4-10-19(11-5-1)16-22(17-20-12-6-2-7-13-20)18-21-14-8-3-9-15-21/h1-15H,16-18H2
7650-89-7Relevant articles and documents
Synthesis of phosphiranes
Kolodyazhnaya,Kolodyazhnyi
, p. 436 - 440 (2015/04/14)
Phosphiranes, three-membered phosphorus-containing heterocycles, have been prepared via reaction of tertiary phosphines dilithium derivatives with carbon tetrachloride. The elaborated method can be applied for preparation of some phosphiranes which are not easily accessible.
Synthesis, characterization and reactivity of tribenzylphosphine rhodium and iridium complexes
Landaeta, Vanessa R.,Peruzzini, Maurizio,Herrera, Verónica,Bianchini, Claudio,Sánchez-Delgado, Roberto A.,Goeta, Andrés E.,Zanobini, Fabrizio
, p. 1039 - 1050 (2007/10/03)
New rhodium and iridium complexes, with the formula [MCl(PBz 3)(cod)] [M = Rh (1), Ir (2)] and [M(PBz3) 2(cod)]PF6 [M = Rh (3), Ir (4)] (cod = 1,5-cyclooctadiene), stabilized by the tribenzylphosphine ligand (PBz 3) were synthesized and characterized by elemental analysis and spectroscopic methods. The molecular structures of 1 and 2 were determined by single-crystal X-ray diffraction. The addition of pyridine to a methanol solution of 1or 2, followed by metathetical reaction with NH4PF 6, gave the corresponding derivatives [M(py)(PBz3)(cod)] PF6 [M = Rh (5), Ir (6)]. At room temperature in CHCl3 solution, 4 converted spontaneously to the ortho-metallated complex [IrH(PBz3)(cod){η2-P,C-(C6H 4CH2)PBz2}]PF6 (7) as a mixture of cis/trans isomers via intramolecular C-H activation of a benzylic phenyl ring. The reaction of 3 or 4 with hydrogen in coordinating solvents gave the dihydrido bis(solvento) derivative [M(H)2(S)2(PBz3) 2]PF6 (M = Rh, Ir; S = acetone, acetonitrile, THF), that transformed into the corresponding dicarbonyls [M(H)2(CO) 2(PBz3)2]PF6 by treatment with CO. Analogous cis-dihydrido complexes [M(H)2(THF)2(py) (PBz3)2]PF6 (M = Rh, Ir) were observed by reaction of the py derivatives 5 and 6 with H2.
Hydrogenolysis process
-
, (2008/06/13)
A process of hydrogenolysis utilizing a new catalyst consisting of a palladium phosphine complex, the phosphien having a pKa greater than or equal to 6, a chlorinated aromatic compound and hydrogen.
