765937-65-3

Basic information

• Product Name: 2-Furancarboxaldehyde,5-(4-ethylphenyl)-(9CI)
• Synonyms: 2-Furancarboxaldehyde,5-(4-ethylphenyl)-(9CI)
• CAS NO: 765937-65-3
• Molecular Formula: C₁₃H₁₂O₂
• Molecular Weight: 200.23318
• Product Categories: ETHYL
• Mol File: 765937-65-3.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-Furancarboxaldehyde,5-(4-ethylphenyl)-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Furancarboxaldehyde,5-(4-ethylphenyl)-(9CI)(765937-65-3)
• EPA Substance Registry System: 2-Furancarboxaldehyde,5-(4-ethylphenyl)-(9CI)(765937-65-3)

Safety Data

• Hazardous Substances Data: 765937-65-3(Hazardous Substances Data)

Upstream product

• 1899-24-7 5-bromo-2-furancarboxaldehyde 
• 63139-21-9 4-ethylphenylboronic acid 

Downstream Products

• 765937-71-1 3-[5-(4-ethylphenyl)-2-furyl]acrylic acid 
• 1427538-45-1 2-((5Z)-5-{[5-(4-ethylphenyl)-2-furyl]methylene}-4-oxo-2-thioxo-1,3-thiazolidin-3-yl)succinic acid 

Relevant articles and documents

CYCLIC CARBOXYLIC ACID RHODANINE DERIVATIVES FOR THE TREATMENT AND PREVENTION OF TUBERCULOSIS

Disclosed are methods for the prevention or treatment of tuberculosis in a subject infected with Mycobacterium tuberculosis by administering rhodanine derivatives of formula (I), as well as some novel such compounds. Other embodiments are also disclosed.

Structure-activity relationships of novel anti-malarial agents. Part 4: N-(3-Benzoyl-4-tolylacetylaminophenyl)-3-(5-aryl-2-furyl)acrylic acid amides

In a previous report, we have described novel anti-malarial compounds based on a 2,5-diaminobenzophenone scaffold. Here, we have invesigated acryloyl derivatives carrying a biaryl structure consisting of a terminal aryl residue and a central 2-furyl ring. Several compounds were obtained in the series of para-substituted phenylfurylacryloyl derivatives that displayed improved anti-malarial activity in comparison to earlier described derivatives. From the structure-activity relationships it can be deduced that there has to be a lipophilic moiety in the para-position of the terminal phenyl residue. Furthermore, there are indications that, alternatively, activity may benefit from the presence of a polar moiety with hydrogen bond acceptor properties.