76598-06-6

Basic information

• Product Name: CefuroxiMe Axetil iMpurity C
• Synonyms: CefuroxiMe Axetil iMpurity C;Cefuroxime Axetil EP Impurity C(Cefuroxime Sodium EP Impurity D);Cefuroxime Axetil Impurity C (85%);[6R-[6α,7β(Z)]]-7-[[2-Furanyl(methoxyimino)acetyl]amino]-8-oxo-3-[[[[(trichloroacetyl)amino]carbonyl]oxy]methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid;Cefuroxime Axetil EP Impurity C;Cefuroxime Sodium EP Impurity D
• CAS NO: 76598-06-6
• Molecular Formula: C18H15Cl3N4O9S
• Molecular Weight: 569.7571
• Product Categories: Chiral Reagents, Heterocycles, Impurities, Pharmaceuticals, Intermediates & Fine Chemicals, Sulfur & Selenium Compounds
• Mol File: 76598-06-6.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• Density: 1.82±0.1 g/cm3(Predicted)
• Storage Temp.: Hygroscopic, -20°C Freezer, Under inert atmosphere
• Solubility: DMSO (Slightly), Methanol (Slightly)
• PKA: 2.51±0.50(Predicted)
• CAS DataBase Reference: CefuroxiMe Axetil iMpurity C(CAS DataBase Reference)
• NIST Chemistry Reference: CefuroxiMe Axetil iMpurity C(76598-06-6)
• EPA Substance Registry System: CefuroxiMe Axetil iMpurity C(76598-06-6)

Safety Data

• Hazardous Substances Data: 76598-06-6(Hazardous Substances Data)

Usage

Description

N-(2,2,2-Trichloroacetyl)cefuroxime, also known as Cefuroxime Axetil Impurity C, is a metabolite of Cefuroxime Axetil (C248065). It is derived from an injectable second-generation cephalosporin antibiotic, which is recognized for its exceptional antibacterial properties. N-(2,2,2-Trichloroacetyl)cefuroxime plays a significant role in the pharmaceutical industry due to its association with a widely used antibiotic.

Uses

Used in Pharmaceutical Industry:
N-(2,2,2-Trichloroacetyl)cefuroxime is used as an impurity reference substance for the development and validation of analytical methods in the pharmaceutical sector. Its application is crucial for ensuring the quality, safety, and efficacy of Cefuroxime Axetil, an injectable second-generation cephalosporin antibiotic with excellent antibacterial activity.
Used in Quality Control:
In the pharmaceutical industry, N-(2,2,2-Trichloroacetyl)cefuroxime serves as a critical component in quality control processes. It helps in the assessment of the purity and potency of Cefuroxime Axetil, ensuring that the final product meets the required standards and is safe for use in medical treatments.
Used in Research and Development:
N-(2,2,2-Trichloroacetyl)cefuroxime is also utilized in research and development activities related to the improvement of existing antibiotics and the development of new ones. Understanding the properties and behavior of N-(2,2,2-Trichloroacetyl)cefuroxime can contribute to the advancement of antibiotic therapies and the fight against bacterial resistance.