76599-46-7

Basic information

• Product Name: 1-adamantyl-4,5-di(phenyl)-1H-1,2,3-triazole
• CAS NO: 76599-46-7
• Molecular Weight: 355.483
• Mol File: 76599-46-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-adamantyl-4,5-di(phenyl)-1H-1,2,3-triazole(CAS DataBase Reference)
• NIST Chemistry Reference: 1-adamantyl-4,5-di(phenyl)-1H-1,2,3-triazole(76599-46-7)
• EPA Substance Registry System: 1-adamantyl-4,5-di(phenyl)-1H-1,2,3-triazole(76599-46-7)

Safety Data

• Hazardous Substances Data: 76599-46-7(Hazardous Substances Data)

Upstream product

• 24886-73-5 1-Azidoadamantane 
• 501-65-5 diphenyl acetylene 

Relevant articles and documents

Oxidative nitrene transfer from azides to alkynes via Ti(ii)/Ti(iv) redox catalysis: Formal [2+2+1] synthesis of pyrroles

Catalytic oxidative nitrene transfer from azides with the early transition metals is rare, and has not been observed without the support of redox noninnocent spectator ligands. Here, we report the formal [2+2+1] coupling of azides and alkynes via TiII/TiIV redox catalysis from simple Ti halide imido precatalysts. These reactions yield polysubstituted N-alkyl pyrroles, including N-benzyl protected pyrroles and rare examples of very electron rich pentaalkyl pyrroles. Mechanistic analysis reveals that [2+2+1] reactions with bulky azides have different mechanistic features from previously-reported reactions using azobenzene as a nitrene source.