76618-03-6

Basic information

• Product Name: 3-[4-(1H-benzimidazol-2-yl)phenyl]-6-bromo-2-phenylquinazolin-4(3H)-one
• CAS NO: 76618-03-6
• Molecular Formula: C₂₇H₁₇BrN₄O
• Molecular Weight: 493.3541
• Mol File: 76618-03-6.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 719.8°C at 760 mmHg
• Flash Point: 389.1°C
• Density: 1.49g/cm³
• Vapor Pressure: 1.44E-20mmHg at 25°C
• Refractive Index: 1.739
• CAS DataBase Reference: 3-[4-(1H-benzimidazol-2-yl)phenyl]-6-bromo-2-phenylquinazolin-4(3H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-[4-(1H-benzimidazol-2-yl)phenyl]-6-bromo-2-phenylquinazolin-4(3H)-one(76618-03-6)
• EPA Substance Registry System: 3-[4-(1H-benzimidazol-2-yl)phenyl]-6-bromo-2-phenylquinazolin-4(3H)-one(76618-03-6)

Safety Data

• Hazardous Substances Data: 76618-03-6(Hazardous Substances Data)

Upstream product

• 2963-77-1 4-(1H-benzimidazol-2-yl)aniline 
• 66387-70-0 6-bromo-2-phenyl-4H-benzo[2,3-d]-1,3-oxazin-4-one 

Relevant articles and documents

Search for potential anticonvulsant agents. Synthesis of 2-phenyl/methyl-3-[o-, m- or p-(benzimidazol-2'-yl)phenyl]-6 or 6,8-substituted/unsubstituted quinazolin(3H)-4-ones.

Sixteen new quinazolones were synthesized by the condensation of substituted 4-oxo-3,1-benzoxazines and 2-(o-, m- or p-aminophenyl)benzimidazoles. All the sixteen compounds were tested for anticonvulsant activity in mice against pentylenetetrazole induced convulsions. Except for five compounds in which there was no protection, the others showed protection ranging from 20 to 80%.