76639-77-5

Basic information

• Product Name: 2-methyl-7-<(p-acetamidobenzene)sulfonyl>-2,7-diazabicyclo<4.1.0>hept-3-ene
• Synonyms: 2-methyl-7-<(p-acetamidobenzene)sulfonyl>-2,7-diazabicyclo<4.1.0>hept-3-ene
• CAS NO: 76639-77-5
• Molecular Weight: 307.373
• Mol File: 76639-77-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-methyl-7-<(p-acetamidobenzene)sulfonyl>-2,7-diazabicyclo<4.1.0>hept-3-ene(CAS DataBase Reference)
• NIST Chemistry Reference: 2-methyl-7-<(p-acetamidobenzene)sulfonyl>-2,7-diazabicyclo<4.1.0>hept-3-ene(76639-77-5)
• EPA Substance Registry System: 2-methyl-7-<(p-acetamidobenzene)sulfonyl>-2,7-diazabicyclo<4.1.0>hept-3-ene(76639-77-5)

Safety Data

• Hazardous Substances Data: 76639-77-5(Hazardous Substances Data)

Upstream product

• 33666-44-3 N-methyl-1,4-dihydropyridine 
• 2158-14-7 4-acetamidobenzenesulfonyl azide 

Relevant articles and documents

Some Reactions of 1,4-Dihydropyridines with Organic Azides. Synthesis of 2,7-Diazabicyclohept-3-enes with Analgesic and Antiprotozoal Activity

The 1,3-dipolar cycloaddition reaction of 1,4-dihydropyridines, 2, with organic azides, 3, afford 2,7-diazabicyclohept-3-enes, 4, which exhibit significant analgesic and antiprotozoal activities.The most active analgesics, 4a and 4c, were more potent than aspirin or dextropropoxyphene.Diazabicyclohept-3-enes 4a-e exert potent antiprotozoal activity, inhibiting growth of Trichomonas vaginalis at concentrations of less than 10 μg/mL of medium.The broad spectrum pharmacological screen also revealed moderate hypoglycemic (4a), antiinflammatory (4c), antidepressant (4d and 4e) and antihistaminic (4f) activities.