766529-96-8

Basic information

• Product Name: [(4E)-(1R,3R,5R)-3-[(tert-butyldimethylsilyl)oxy]-1,5-dihydroxy-4-[3-(methoxymethoxy)propylidene]cyclohexyl]methanol
• Synonyms: [(4E)-(1R,3R,5R)-3-[(tert-butyldimethylsilyl)oxy]-1,5-dihydroxy-4-[3-(methoxymethoxy)propylidene]cyclohexyl]methanol
• CAS NO: 766529-96-8
• Molecular Weight: 376.566
• Mol File: 766529-96-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: [(4E)-(1R,3R,5R)-3-[(tert-butyldimethylsilyl)oxy]-1,5-dihydroxy-4-[3-(methoxymethoxy)propylidene]cyclohexyl]methanol(CAS DataBase Reference)
• NIST Chemistry Reference: [(4E)-(1R,3R,5R)-3-[(tert-butyldimethylsilyl)oxy]-1,5-dihydroxy-4-[3-(methoxymethoxy)propylidene]cyclohexyl]methanol(766529-96-8)
• EPA Substance Registry System: [(4E)-(1R,3R,5R)-3-[(tert-butyldimethylsilyl)oxy]-1,5-dihydroxy-4-[3-(methoxymethoxy)propylidene]cyclohexyl]methanol(766529-96-8)

Safety Data

• Hazardous Substances Data: 766529-96-8(Hazardous Substances Data)

Upstream product

• 665-27-0 1,5-quinide 
• 163217-18-3 (1R,3R,4S,5R)-3-[(tert-butyldimethylsilyl)oxy]-1,4-dihydroxy-6-oxa-bicyclo[3.2.1]octan-7-one 
• 78365-43-2 1-bromo-3-(methoxymethoxy)propane 
• 77-95-2 D-(-)-quinic acid 
• 766529-88-8 (1R,3R,5R)-1-acetoxy-3-[(tert-butyldimethylsilyl)oxy]-6-oxa-bicyclo[3.2.1]octane-4,7-dione 
• 766529-89-9 (4E)-(1R,3R,5R)-1-acetoxy-3-[(tert-butyldimethylsilyl)oxy]-6-oxa-4-[3'-(methoxymethoxy)propylidene]bicyclo[3.2.1]octan-7-one 

Downstream Products

• 766529-90-2 (3R,5R)-3,5-bis[(tert-butyldimethylsilyl)oxy]-4-[3-(methoxymethoxy)propylidene]cyclohexanone 
• 766529-97-9 (4E)-(3R,5R)-3-[(tert-butyldimethylsilyl)oxy]-5-hydroxy-4-[3-(methoxymethoxy)propylidene]cyclohexanone 

Relevant articles and documents

New 2-alkylidene 1α,25-dihydroxy-19-norvitamin D3 analogues of high intestinal activity: Synthesis and biological evaluation of 2-(3′-alkoxypropylidene) and 2-(3′-hydroxypropylidene) derivatives

In a search for novel vitamin D compounds of potential therapeutic value, E- and Z-isomers of 1α,25-dihydroxy-2-(3′-hydroxypropylidene)-19- norvitamin D3, as well as a derivative of the former compound possessing a 3′-(methoxymethoxy)propyliden

2-PROPYLIDENE-19-NOR-VITAMIN D COMPOUNDS

2-propylidene-19-nor-vitamin D compounds are disclosed as well as pharmaceutical uses for these compounds and methods of synthesizing these compounds. These compounds are characterized by high bone calcium mobilization activity and high intestinal calcium