767-83-9 Usage
Class
Heterocyclic compound
Derivative of
Pyridine
Appearance
Unknown, but likely a solid or liquid depending on the conditions
Odor
Unknown, but may have a characteristic chemical odor
Solubility
Unknown, but likely soluble in organic solvents such as ethanol or acetone
Boiling point
Unknown, but can be estimated based on similar compounds
Melting point
Unknown, but can be estimated based on similar compounds
Density
Unknown, but can be estimated based on similar compounds
Polarity
Unknown, but likely polar due to the presence of the nitrile group
Reactivity
Unknown, but may react with strong acids, bases, or reducing agents
Uses
Intermediate in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds; potential use as a corrosion inhibitor and as a reagent in organic chemistry reactions
Pharmacological properties
Potential antioxidant and possible treatment for neurodegenerative diseases
Research and industry importance
Wide range of applications in various fields of research and industry
Safety
Unknown, but should be handled with care due to its potential reactivity and unknown toxicity
Environmental impact
Unknown, but may have an impact on the environment if not properly disposed of or if released in large quantities
Regulatory status
Unknown, but may be subject to regulations depending on its intended use and concentration in products
Synthesis
Can be synthesized through various methods, such as the reaction of a pyridine derivative with a methylating agent or through the condensation of a suitable aldehyde or ketone with ammonia and an alkyl halide.
Check Digit Verification of cas no
The CAS Registry Mumber 767-83-9 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 7,6 and 7 respectively; the second part has 2 digits, 8 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 767-83:
(5*7)+(4*6)+(3*7)+(2*8)+(1*3)=99
99 % 10 = 9
So 767-83-9 is a valid CAS Registry Number.
767-83-9Relevant articles and documents
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Cook
, p. 1435,1437 (1963)
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Studies on the stereochemistry of 1,2,6-trimethyl-4-piperidone
Diwischek, Florian,Arnone, Mario,Engels, Bernd,Holzgrabe, Ulrike
, p. 6993 - 7001 (2007/10/03)
In the effort to create new derivatives of analgesically active spiropiperidines intermediate 1,2,6-trimethyl-4-piperidone was synthesized. The substitution of the skeleton gives rise to configurational as well as conformational isomerism. Despite the symmetry of 1,2,6-trimethyl-4-piperidone two different sets of signals were present in the 1H and 13C NMR spectra. They were supposed to arise from a cis/trans mixture of 1,2,6-trimethyl-4-piperidone. In contrast to this explanation only two signals of the methyl groups and hydrogens at carbon atoms 2 and 6 were observed in the 1H and 13C NMR spectra, normally expecting one for the cis- and two for the trans-isomer. To solve this discrepancy, the kind of isomeric mixture of 1,2,6-trimethyl-4-piperidone leading to the 1H and 13C NMR spectra was examined. Energy differences between chair conformations of both the cis- and the trans-isomer of 1,2,6-trimethyl-4- piperidone and the potential energy surface of the equilibration process of the trans-isomer of 1,2,6-trimethyl-4-piperidone between its chair conformers were determined by quantum chemical calculations. The barrier height of the equilibration process was measured by high and low temperature NMR measurements to confirm the theoretical outcome. The results of all investigations agree nicely and proved a cis-/trans-mixture of 1,2,6-trimethyl-4-piperidone being present at room temperature.
