76716-11-5

Basic information

• Product Name: 1,3-Benzenedicarboxylic acid, 2-hydroxy-4,6-dimethyl-, dimethyl ester
• Synonyms: dimethyl 2-hydroxy-4,6-dimethylisophthalate;1,3-Benzenedicarboxylic acid,2-hydroxy-4,6-dimethyl-,dimethyl ester;dimethyl 4,6-dimethyl-2-hydroxyisophthalate;2,6-Dimethoxycarbonyl-3,5-dimethylphenol;1,3-benzenedicarboxylic acid 2-hydroxy-4,6-dimethyl-1,3-dimethyl ester
• CAS NO: 76716-11-5
• Molecular Formula: C12H14O5
• Molecular Weight: 238.24
• Mol File: 76716-11-5.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 1,3-Benzenedicarboxylic acid, 2-hydroxy-4,6-dimethyl-, dimethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-Benzenedicarboxylic acid, 2-hydroxy-4,6-dimethyl-, dimethyl ester(76716-11-5)
• EPA Substance Registry System: 1,3-Benzenedicarboxylic acid, 2-hydroxy-4,6-dimethyl-, dimethyl ester(76716-11-5)

Safety Data

• Hazardous Substances Data: 76716-11-5(Hazardous Substances Data)

Upstream product

• 1830-54-2 3-oxopentanedioic acid dimethyl ester 
• 54716-01-7 (E)-4-(dimethylamino)pent-3-en-2-one 
• 123-54-6 acetylacetone 

Downstream Products

• 1333471-42-3 4,6-dimethyl-2-methoxymethoxyisophthalic acid dimethyl ester 
• 1333471-50-3 2,6-diformyl-3,5-bis(2,5,8,11-tetraoxadodecyl)phenyl methoxymethyl ether 
• 1333471-48-9 2,6-dihydroxymethyl-3,5-bis(2,5,8,11-tetraoxadodecyl)phenyl methoxymethyl ether 
• 1333471-46-7 2-methoxymethoxy-4,6-bis(2,5,8,11-tetraoxadodecyl)isophthalic acid dimethyl ester 
• 1333471-44-5 4,6-bis(bromomethyl)-2-methoxymethoxyisophthalic acid dimethyl ester 
• 1333471-54-7 2,6-diformyl-3,5-bis(2,5,8,11-tetraoxadodecyl)phenyl trifluoromethanesulfonate 
• 1333471-52-5 2,6-diformyl-3,5-bis(2,5,8,11-tetraoxadodecyl)phenol 
• 432043-04-4 2,6-bis-bromomethyl-3,5-dimethyl-phenol 
• 22002-36-4 2,6-bis(hydroxymethyl)-3,5-dimethylphenol 
• 99059-33-3 4,6-dimethyl-2-hydroxy-isophthalic acid 
• 527-35-5 2,3,5,6-tetramethylphenol 
• 17362-16-2 4-bromo-2,3,5,6-tetramethylphenol 
• 906623-25-4 4-[4-(methoxymethoxy)-2,3,5,6-tetramethylphenyl]pyridine 
• 906623-31-2 2,3,5,6-tetramethyl-4-(pyridin-4'-yl)phenol 

Relevant articles and documents

Syntheses of extreme sterically hindered 4-methoxyboronic acids

4-Iodoanisoles 3a,b, 3d and 4-bromoanisoles 4a-d were readily obtained. An extreme steric hindrance precluded obtaining 3c. Catalytic borylation of 3a,b, 3d followed by hydrolysis of boronic ester 26a,b, 26d easily provided the boronic acids 5a,b, 5d. Com

Effect of ligand structure on the zinc-catalyzed Henry reaction. Asymmetric syntheses of (-)-denopamine and (-)-arbutamine

(Matrix presented) Syntheses of variously modified ligands for the dinuclear zinc catalysts for the asymmetric aldol and nitroaldol (Henry) reactions are reported. Catalytic enantioselective nitroaldol reactions promoted by these modified ligands led to efficient syntheses of the β-preceptor agonists (-)-denopamine and (-)-arbutamine.

A New Aromatic Annelation Reaction with Two Synthons, Enaminones and 3-Oxoglutarate. Studies on the β-Carbonyl Compounds Connected with β-Polyketides. VIII

Reactions of the enaminones 1 with dimethyl 3-oxoglutarate in the presence of KF-AcOH or AcONa-AcOH and 18-crown-6 gave the dimethyl 2-hydroxy-1,3-benzenedicarboxylates 3, providing a new aromatic annelation reaction.Keywords - enaminone; dimethyl 3-oxoglutarate; buffer catalysis; aromatic annelation; dimethyl 2-hydroxy-1,3-benzenedicarboxylate