76758-01-5

Basic information

• Product Name: N-TRIPHENYLMETHYLTHIOUREA
• Synonyms: N-TRIPHENYLMETHYLTHIOUREA;TIMTEC-BB SBB008389;TRITYLTHIOUREA;Thiourea,(triphenylMethyl)- (9CI);Aids-247090;N-Triphenylmethylthiourea Fr-1341
• CAS NO: 76758-01-5
• Molecular Formula: C₂₀H₁₈N₂S
• Molecular Weight: 318.44
• Product Categories: Miscellaneous Reagents;Sulfur & Selenium Compounds
• Mol File: 76758-01-5.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 493.1°C at 760 mmHg
• Flash Point: 252°C
• Appearance: /
• Density: 1.193g/cm³
• Vapor Pressure: 7.24E-10mmHg at 25°C
• Refractive Index: 1.66
• Solubility: Methanol
• CAS DataBase Reference: N-TRIPHENYLMETHYLTHIOUREA(CAS DataBase Reference)
• NIST Chemistry Reference: N-TRIPHENYLMETHYLTHIOUREA(76758-01-5)
• EPA Substance Registry System: N-TRIPHENYLMETHYLTHIOUREA(76758-01-5)

Safety Data

• Hazardous Substances Data: 76758-01-5(Hazardous Substances Data)

Usage

Uses

Protected Thiourea.

InChI:InChI=1/C20H18N2S/c21-19(23)22-20(16-10-4-1-5-11-16,17-12-6-2-7-13-17)18-14-8-3-9-15-18/h1-15H,(H3,21,22,23)

Upstream product

• 76-83-5 trityl chloride 
• 17356-08-0 thiourea 
• 76-84-6 triphenylmethyl alcohol 
• 859326-50-4 N-benzoyl-N'-trityl-thiourea 

Downstream Products

• 76758-02-6 N-(tosylmethyl)-N'-(triphenylmethyl)thiourea 
• 14078-30-9 N,N'-Ditrytylurea 
• 76758-07-1 5-phenyl-2-<(triphenylmethyl)amino>oxazole 
• 76758-13-9 5-p-chlorophenyl-2-triphenylmethylaminooxazole 
• 76758-11-7 5-p-methoxyphenyl-2-triphenylmethylaminooxazole 
• 76758-09-3 5-p-nitrophenyl-2-triphenylmethyloxazole 
• 76757-96-5 N-(tosylmethyl)-N'-(triphenylmethyl)carbodiimide 
• 76758-15-1 N-(tosylmethyl)-N'-(triphenylmethyl)urea 
• 302964-24-5 2-amino-N-(2-chloro-6-methylphenyl)-1.3-thiazole-5-carboxamide 

Relevant articles and documents

PROCESS FOR PREPARING N-(2-CHLORO-6-METHYLPHENYL)-2-[[6-[4-(2-HYDROXYETHYL)-1-PIPERAZINYL]-2-METHYL-4-PYRIMIDINYL]AMINO] -5-THIAZOLECARBOXAMIDE AND RELATED METABOLITES THEREOF

The present invention is directed to process for the preparation of metabolites as well as the parent compound of N-(2-chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl] amino]-5-thiazolecarboxamide, the compound of formula (I).

Synthesis of N-(Tosylmethyl)carbodiimides and Their Application in the Synthesis of 2-Amino-1,3-oxazoles from Aldehydes

A series of N-(tosylmethyl)carbodiimides (TosCH2N=C=NR1, 3) have been prepared from the corresponding thioureas.Carbodiimides 3 with R1 = triphenylmethyl or tert-butyl are useful synthons in a new one-step synthesis of 2-(alkylamino)-1,3-oxazoles 10 from aromatic aldehydes.Acid-induced removal of the triphenylmethyl group from 10 gives 2-amino-1,3-oxazoles (11).