76877-59-3

Basic information

• Product Name: (E)-2-Benzyl-3-ethoxy-acrylonitrile
• CAS NO: 76877-59-3
• Molecular Weight: 187.241
• Mol File: 76877-59-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (E)-2-Benzyl-3-ethoxy-acrylonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-2-Benzyl-3-ethoxy-acrylonitrile(76877-59-3)
• EPA Substance Registry System: (E)-2-Benzyl-3-ethoxy-acrylonitrile(76877-59-3)

Safety Data

• Hazardous Substances Data: 76877-59-3(Hazardous Substances Data)

Upstream product

• 61310-53-0 3-ethoxyacrylonitrile 
• 100-39-0 benzyl bromide 

Downstream Products

• 108044-72-0 4-amino-5-benzyl-1H-pyrimidin-2-one 
• 158495-74-0 4-amino-5-benzyl-1-methylpyrimidine-2-thione 

Relevant articles and documents

ALKYLATION OF 3-ETHOXY-2-LITHIOACRYLONITRILE: SYNTHESIS OF 5-ALKYLCYTOSINES

The utility of commercially available, inexpensive 3-ethoxyacrylonitrile (1) as a precursor for the synthesis of 5-alkylcytosines was investigated.Metalation of 1 affords a 2-lithio derivative of sufficient stability to allow alkylation with allylic or benzylic bromides and primary iodides which are unbranched at the β-position.The alkylated derivatives are converted to 5-alkylcytosines in modest yield by exposure to sodium ethoxide and urea in ethanol.