76893-32-8

Basic information

• Product Name: 3-Bromomethyl-2,5-dihydro-2,2,5,5-tetramethyl-1H-pyrrol-1-yloxy
• Synonyms: 3-Bromomethyl-2,5-dihydro-2,2,5,5-tetramethyl-1H-pyrrol-1-yloxy;4-BroMoMethyl-2,5-dihydro-2,2,5,5-tetraMethyl-1H-pyrrol-1-yloxy
• CAS NO: 76893-32-8
• Molecular Formula: C₉H₁₅BrNO
• Molecular Weight: 233.1255
• Product Categories: Intermediates;Spin Labeling Compounds
• Mol File: 76893-32-8.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 250.487°C at 760 mmHg
• Flash Point: 105.291°C
• Appearance: /
• Density: 1.307g/cm³
• Vapor Pressure: 0.007mmHg at 25°C
• Refractive Index: 1.518
• Storage Temp.: -20°C Freezer, Under Inert Atmosphere
• Solubility: Chloroform (Slightly), Methanol (Slightly)
• CAS DataBase Reference: 3-Bromomethyl-2,5-dihydro-2,2,5,5-tetramethyl-1H-pyrrol-1-yloxy(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Bromomethyl-2,5-dihydro-2,2,5,5-tetramethyl-1H-pyrrol-1-yloxy(76893-32-8)
• EPA Substance Registry System: 3-Bromomethyl-2,5-dihydro-2,2,5,5-tetramethyl-1H-pyrrol-1-yloxy(76893-32-8)

Safety Data

• Hazardous Substances Data: 76893-32-8(Hazardous Substances Data)

Usage

Uses

Intermediate in the production of spin labelled compounds

InChI:InChI=1/C9H16BrNO/c1-8(2)5-7(6-10)9(3,4)11(8)12/h5,12H,6H2,1-4H3

Upstream product

• 76893-29-3 2,5-dihydro-2,2,5,5-tetramethyl-3-({[(4-methylphenyl)sulfonyl]oxy}methyl)-1H-pyrrol-1-yloxy 
• 76893-27-1 (1-oxyl-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-3-yl)methyl methanesulfonate 
• 55738-75-5 (2,5-dihydro-2,2,5,5-tetramethyl-1-oxyl-1H-pyrrol-3-yl)methanol 
• 826-36-8 2,2,6,6-Tetramethyl-4-piperidone 
• 19971-12-1 3,5-Dibromo-4-oxo-2,2,6,6-tetramethylpiperidine Hydrobromide 
• 70473-81-3 2,2,5,5-tetramethyl-2,5-dihydropyrrole-3-carboxylic acid methyl ester 
• 2154-32-7 methyl 1-oxyl-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-3-carboxylate radical 

Downstream Products

• 82954-73-2 C₂₆H₃₁N₂O₃ 
• 76893-33-9 3-Iodomethyl-2,2,5,5-tetramethyl-2,5-dihydropyrrole-1-oxyl 
• 105843-26-3 C₂₂H₃₀NO₅ 
• 819837-70-2 6-amino-1-(1-oxyl-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-3-ylmethyl)-5-cyclopentanoylamido-3-propyluracil 
• 851025-46-2 2-methyl-3-[3,5-diiodo-4-(1-oxyl-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-3-ylmethyl)oxybenzoyl]benzofuran 
• 906465-15-4 2,2,5,5-tetramethyl-3-[4-(2,3,4-trimethoxybenzyl)piperazin-1-ylmethyl]-2,5-dihydro-1H-pyrrol-1-yloxyl radical 
• 851068-84-3 [3,5-diiodo-4-(2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-3-ylmethoxy)-phenyl]-(2-methyl-benzofuran-3-yl)-methanone 
• 851025-48-4 2-methyl-3-(3,5-diiodo-4-{2-[N-ethyl,N-(1-oxyl-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-3-ylmethyl)amino]ethyl}oxybenzoyl)benzofuran 
• 851025-45-1 2-butyl-3-(3,5-diiodo-4-{2-[N-ethyl,N-(1-oxyl-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-3-ylmethyl)amino]ethyl}oxybenzoyl)benzofuran 
• 82954-79-8 ethyl 2-benzyloxycarbonylamino-3-(1-oxyl-2,2,5,5-tetramethyl-3-pyrrolin-3-yl)propionate 
• 105843-20-7 5-phenyl-5-<(1-oxyl-2,2,5,5-tetramethyl-3-pyrroline-3-yl)methyl>barbituric acid 
• 105843-24-1 2-(1-Hydroxy-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-3-ylmethyl)-2-phenyl-malonic acid diethyl ester; hydrochloride 
• 1117727-32-8 benzyl 4,6-O-benzylidene-2-deoxy-2-steraoylamido-3-O-(1-oxyl-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-3-yl)methyl-α-D-glucopyranoside 
• 791591-62-3 4-(1-oxyl-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-3-ylmethoxy)-3-methoxybenzaldehyde 

Relevant articles and documents

Synthesis of Chiral Spin-Labeled Amino Acids

Spin-labeled amino acids (SLAAs) are often used to determine intermolecular distances and conformations in proteins via double electron-electron resonance. Currently available SLAAs can be difficult to incorporate selectively and have little resemblance to natural side chains in proteins. Enantioselective synthesis of three spin-labeled l-amino acids is described, starting from readily available 2,2,6,6-tetramethyl-4-piperidinone. These SLAAs better replicate canonical residues in proteins and aim for biological incorporation via genetic incorporation or solid-phase peptide synthesis.