76896-60-1

Basic information

• Product Name: 2,4(1H,3H)-Pyrimidinedione, 3-methyl-6-[(4-methylphenyl)amino]-
• CAS NO: 76896-60-1
• Molecular Formula: C12H13N3O2
• Molecular Weight: 231.254
• Mol File: 76896-60-1.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 2,4(1H,3H)-Pyrimidinedione, 3-methyl-6-[(4-methylphenyl)amino]-(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4(1H,3H)-Pyrimidinedione, 3-methyl-6-[(4-methylphenyl)amino]-(76896-60-1)
• EPA Substance Registry System: 2,4(1H,3H)-Pyrimidinedione, 3-methyl-6-[(4-methylphenyl)amino]-(76896-60-1)

Safety Data

• Hazardous Substances Data: 76896-60-1(Hazardous Substances Data)

Upstream product

• 106-49-0 p-toluidine 
• 4318-56-3 3-methyl-6-chlorouracil 

Downstream Products

• 129749-70-8 6-benzyloxy-3-methyl-10-p-tolyl-5-deazaflavin 
• 76896-48-5 10-p-tolyl-3-methylpyrimido<4,5-b>-quinoline-2,4(3H,10H)-dione 
• 129749-65-1 6-chloro-3-methyl-10-p-tolyl-5-deazaflavin 
• 129749-68-4 6-dimethylamino-3-methyl-10-p-tolyl-5-deazaflavin 
• 76896-36-1 C₃₁H₃₀N₆O₄ 
• 133373-74-7 3-Methyl-10-p-tolyl-10H-benzo[g]pteridine-2,4-dione 
• 128772-79-2 1,5-dihydro-6-hydroxy-3-methyl-10-p-tolyl-5-deazaflavin 
• 129749-72-0 6--1,5-dihydro-3-methyl-10-p-tolyl-5-deazaflavin 
• 129749-71-9 6--3-methyl-10-p-tolyl-5-deazaflavin 
• 129749-67-3 3-methyl-10-p-tolyl-6-methylsulfonyl-5-deazaflavin 
• 129749-66-2 3-methyl-10-p-tolyl-6-methylthio-5-deazaflavin 
• 92978-43-3 6-benzoyl-1,2,3,4,7,8-hexahydro-3-methyl-8(4-methylphenyl)-2,4,7-trioxopyrido-<2,3-d>pyrimidine 
• 92978-21-7 3-Methyl-2,4-dioxo-7-phenyl-8-p-tolyl-2,3,4,8-tetrahydro-pyrido[2,3-d]pyrimidine-6-carboxylic acid 
• 79157-26-9 10-(4-Methylphenyl)-3,7-dimethylpyrido<2,3-d:6,5-d'>pyrimidine 

Relevant articles and documents

Autorecycling Oxidation of Alcohols Catalysed by Pyridopyrimidines as an NAD(P)(1+) Model

Two kinds of pyridopyrimidines as new NAD-type redox catalysts, 3,7,10-trisubstituted pyridodipyrimidine-2,4,6,8(1H,3H,7H,10H)-tetraones 6 and 3,8,10-trisubstituted pyridodipyrimidine-2,4,6(3H,7H,10H)-triones 7, have been synthesized by the condensation of 6-(substituted-amino)uracils 9 and 6-(substituted-amino)-2-phenylpyrimidin-4(3H)-ones 11 with appropriate 6-chloro-5-formyluracils 12 or 2,4,6-trichloropyrimidine-5-carbaldehyde 13 in dimethylformamide (DMF) or acetic acid.Compounds 6 and 7 have been found to oxidize a variety of alcohols under neutral conditions (in the absence of base) to yield the corresponding carbonyl compounds, catalytically with a markedly high turnover number.The oxidation yields were promoted remarkably depending upon the presence of lipophilic substituents, particularly due to the presence of longer alkyl groups at the 10-position.These catalysts are so stable that the oxidation reaction proceeds until the substrate is exhausted.

Fluid Solution and Solid-State Electron Nuclear Double Resonance Studies of Flavin Model Compounds and Flavoenzymes

Partially deuterated and various substituted flavin and thiaflavin model compounds have been synthesized.For the first time, high-resolution H, D, and 14N ENDOR and TRIPLE resonance experiments in fluid solution have been performed on the paramagnetic derivatives of these compounds.Additionally, valuable information has been obtained about hyperfine anisotropies and molecular structures from ENDOR in rigid matrices.Solid matrix ENDOR studies of native flavoenzymes, namely, "Old Yellow Enzyme" (NADPH dehydrogenase), two flavodoxins, and a methanol oxidase are reported.The ENDOR matrix signals of the various flavoproteins are different in intensity, suggesting that the microenvironments are remarkably different.Applicabilities and limitations of the ENDOR technique in the studies of flavins and flavoenzymes are discussed.