769-30-2

Basic information

• Product Name: 1,3-BENZODIOXOL-4-YLMETHANOL
• Synonyms: 2H-1,3-benzodioxol-4-ylMethanol;1,3-Benzodioxole-4-methanol;Benzodioxol-4-ylmethanol;1,3-BENZODIOXOL-4-YLMETHANOL;RARECHEM AL BD 0228;(benzo[d][1,3]dioxol-4-yl）methanol;(1,3-Benzodioxol-4-yl)methanol, 2,3-(Methylenedioxy)benzyl alcohol;4-(Hydroxymethyl)-1,3-benzodioxole
• CAS NO: 769-30-2
• Molecular Formula: C₈H₈O₃
• Molecular Weight: 152.15
• Mol File: 769-30-2.mol
• Article Data: 15

Chemical Properties

• Melting Point: 39℃
• Boiling Point: 124 °C
• Flash Point: 127.9±21.5℃
• Appearance: /
• Density: 1.329±0.06 g/cm3 (20 ºC 760 Torr)
• Vapor Pressure: 0.00112mmHg at 25°C
• Refractive Index: 1.594
• Storage Temp.: Inert atmosphere,Room Temperature
• PKA: 14.24±0.10(Predicted)
• CAS DataBase Reference: 1,3-BENZODIOXOL-4-YLMETHANOL(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-BENZODIOXOL-4-YLMETHANOL(769-30-2)
• EPA Substance Registry System: 1,3-BENZODIOXOL-4-YLMETHANOL(769-30-2)

Safety Data

• Safety Statements: 24/25
• Hazardous Substances Data: 769-30-2(Hazardous Substances Data)

Usage

General Description

1,3-Benzodioxol-4-ylmethanol, also known as piperonyl alcohol, is an organic chemical compound commonly used as a fragrance ingredient and insecticide synergist. It is a colorless to pale yellow liquid with a floral, sweet, and slightly spicy odor. This chemical is found in a variety of consumer products, including perfumes, soaps, and air fresheners. In addition, piperonyl alcohol is often used in combination with other insecticides to enhance their effectiveness, particularly against resistant pests. While it has been recognized as generally safe for use in the intended applications, proper handling and storage precautions should always be observed.

InChI:InChI=1/C8H8O3/c9-4-6-2-1-3-7-8(6)11-5-10-7/h1-3,9H,4-5H2

Upstream product

• 33842-16-9 benzo[1,3]dioxole-4-carboxylic acid methyl ester 
• 7797-83-3 2H-benzo[d]1,3-dioxolane-4-carbaldehyde 
• 254973-61-0 benzo[d][1,3]dioxol-5-yl(trimethylsilyl)methanone 
• 24677-78-9 2,3-dihydroxybenzaldehyde 
• 5279-32-3 5,6-dibromo-1,3-benzodioxole 
• 5768-39-8 benzo[1,3]dioxole-4-carboxylic acid 
• 75-16-1 methylmagnesium bromide 
• 23158-06-7 benzo[1,3]dioxole-4-carboxylic acid ethyl ester 
• 880486-80-6 C₁₁H₁₆O₃Si 
• 66411-55-0 2,3-(Methylenedioxy)benzoyl chloride 
• 2411-83-8 methyl-2,3-dihydroxybenzoate 
• 303-38-8 2,3-Dihydroxybenzoic acid 

Downstream Products

• 101417-40-7 4-(bromomethyl)benzo[d][1,3]dioxole 
• 75875-58-0 4-(chloromethyl)benzo[d][1,3]dioxole 
• 669051-20-1 (5-bromo(2H-benzo[d]1,3-dioxolan-4-yl))methoxymethane 
• 101417-41-8 2-<4-isopropoxy-3-methoxy-5-methyl-2-(2',3'-methylenedioxybenzyl)phenyl>-4,4-dimethyl-2-oxazoline 
• 7797-83-3 2H-benzo[d]1,3-dioxolane-4-carbaldehyde 
• 1207280-91-8 C₁₅H₁₅NO₄S 
• 5768-39-8 benzo[1,3]dioxole-4-carboxylic acid 

Relevant articles and documents

Amide derivatives and their medical use

The invention relates to novel amide derivatives shown in a structural formula I in the specification or a pharmaceutically acceptable salt thereof, a medicine composition which takes the compounds as active components, and an application of the derivatives or the pharmaceutically acceptable salt of the derivatives to preparation of analgesia medicines. In the structural formula I, R1 and R2 are a hydrogen atom and a C1-C3 alkyl; R3 is hydrogen atom, C1-C3 alkyl, phenyl or a hydroxyl-substituted alkyl.

Practical and chemoselective reduction of acyl chloride to alcohol by borohydride in aqueous dichloromethane

A simple methodology for the reduction of acid chlorides to their corresponding alcohols has been developed. Various carboxylic acids were converted to alcohols in excellent yields using NaBH4-K2CO3 in a mixed solvent system of dichloromethane and water (1:1) in the presence of a phase-transfer catalyst at low temperature. The importance of the work is its simplicity, selectivity, excellent yield, and very short reaction time. This new reduction condition has proved to be an excellent chemoselective method for a range of acid chlorides in the presence of various functional groups.

Boric acid as cost-effective and recyclable catalyst for trimethylsilyl protection and deprotection of alcohols and phenols

Boric acid has been used as a green, selective and recyclable catalyst for trimethysilylation of alcohols and phenols using hexamethyldisilazane in acetonitrile. Deprotection of trimethylsilyl ethers to their parent alcohols and phenols was also achieved using this catalyst in water at room temperature. The salient features of this methodology are cheap processing, mild acidity conditions, excellent yields of products and easy availability of the catalyst.