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769169-27-9

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  • 5-chloro-N-[(2S)-4,4,4-trifluoro-1-hydroxy-3-(trifluoromethyl)butan-2-yl]thiophene-2-sulfonamide

    Cas No: 769169-27-9

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769169-27-9 Usage

Description

Begacestat, also known as GSI-953, is a selective β-secretase inhibitor that selectively inhibits the cleavage of APP over Notch. It is a pharmaceutical compound with potential applications in the treatment of various diseases.

Uses

Used in Pharmaceutical Industry:
Begacestat is used as a therapeutic agent for treating diseases such as cancer. It works by inhibiting the cleavage of APP over Notch, which can help in the prevention of intestinal secretory metaplasia, a condition that can lead to cancer development.
Additionally, Begacestat's mechanism of action as a β-secretase inhibitor suggests that it may have potential applications in the treatment of other diseases related to the dysregulation of APP processing, such as Alzheimer's disease. However, further research is needed to explore these potential applications.

Check Digit Verification of cas no

The CAS Registry Mumber 769169-27-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 7,6,9,1,6 and 9 respectively; the second part has 2 digits, 2 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 769169-27:
(8*7)+(7*6)+(6*9)+(5*1)+(4*6)+(3*9)+(2*2)+(1*7)=219
219 % 10 = 9
So 769169-27-9 is a valid CAS Registry Number.

769169-27-9 Well-known Company Product Price

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  • Sigma

  • (PZ0187)  GSI-953  ≥98% (HPLC)

  • 769169-27-9

  • PZ0187-5MG

  • 1,062.36CNY

  • Detail
  • Sigma

  • (PZ0187)  GSI-953  ≥98% (HPLC)

  • 769169-27-9

  • PZ0187-25MG

  • 4,288.05CNY

  • Detail

769169-27-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 5-chloro-N-[(2S)-4,4,4-trifluoro-1-hydroxy-3-(trifluoromethyl)butan-2-yl]thiophene-2-sulfonamide

1.2 Other means of identification

Product number -
Other names GSI-953

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:769169-27-9 SDS

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