76945-19-2

Basic information

• Product Name: 2-mercaptobenzaldehyde ethylene acetal
• Synonyms: 2-mercaptobenzaldehyde ethylene acetal
• CAS NO: 76945-19-2
• Molecular Weight: 182.243
• Mol File: 76945-19-2.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-mercaptobenzaldehyde ethylene acetal(CAS DataBase Reference)
• NIST Chemistry Reference: 2-mercaptobenzaldehyde ethylene acetal(76945-19-2)
• EPA Substance Registry System: 2-mercaptobenzaldehyde ethylene acetal(76945-19-2)

Safety Data

• Hazardous Substances Data: 76945-19-2(Hazardous Substances Data)

Upstream product

• 29199-11-9 2-formylthiophenol 
• 107-21-1 ethylene glycol 
• 55164-16-4 2,2'-dithiodibenzaldehyde 
• 4521-31-7 o-hydroxymethyl thiophenol 

Downstream Products

• 125995-48-4 6^A,6^D-bis<2-(1,3-dioxolan-2-yl)phenylthio>cyclomaltoheptaose 
• 76945-20-5 4-(2-[1,3]Dioxolan-2-yl-phenylsulfanyl)-azetidin-2-one 

Relevant articles and documents

Peptide 2-formylthiophenol esters do not proceed through a Ser/Thr ligation pathway, but participate in a peptide aminolysis to enable peptide condensation and cyclization

Peptide thiol salicylaldehyde (SAL) esters unexpectedly do not follow a Ser/Thr ligation pathway to react with peptides containing N-terminal Ser/Thr, but proceed towards a peptide aminolysis in DMSO. The reaction takes place even at a low substrate concentration (1 mM). The method has been successfully used to synthesize several natural cyclic peptides, with a high ratio of monocyclic to dimeric products.

SYNTHESES OF SOME 2,3-BENZO-1-THIAOCTEMS

2,3-Benzo-1-thiaoctems 2, 9, and 6 were synthesized from 4-acetoxyazetidin-2-one (3).Oxidation of 2 and 9 afforded the corresponding sulfoxides and sulfones.The relative stereochemistries of the products were determined from nmr aromatic solvent induced s