770-17-2

Basic information

• Product Name: 2-MORPHOLIN-4-YLACETOHYDRAZIDE
• Synonyms: CHEMBRDG-BB 4022074;2-MORPHOLIN-4-YLACETOHYDRAZIDE;BUTTPARK 162\40-83;4-morpholineacetic acid, hydrazide;2-morpholin-4-ylethanehydrazide;2-morpholin-4-ylacetohydrazide(SALTDATA: FREE);Morpholin-4-yl-acetic acid, hydrazide
• CAS NO: 770-17-2
• Molecular Formula: C₆H₁₃N₃O₂
• Molecular Weight: 159.19
• Mol File: 770-17-2.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 351.2°Cat760mmHg
• Flash Point: 166.2°C
• Appearance: /
• Density: 1.172g/cm³
• Vapor Pressure: 4.18E-05mmHg at 25°C
• Refractive Index: 1.502
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• PKA: 13.01±0.18(Predicted)
• CAS DataBase Reference: 2-MORPHOLIN-4-YLACETOHYDRAZIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-MORPHOLIN-4-YLACETOHYDRAZIDE(770-17-2)
• EPA Substance Registry System: 2-MORPHOLIN-4-YLACETOHYDRAZIDE(770-17-2)

Safety Data

• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 770-17-2(Hazardous Substances Data)

Usage

General Description

2-morpholin-4-ylacetohydrazide, also known as morpholinylacetohydrazide, is a chemical compound with the molecular formula C6H12N4O2. It is a hydrazide derivative, containing a morpholine ring and an acetohydrazide group. 2-morpholin-4-ylacetohydrazide has been studied for its potential use as an antimicrobial and antifungal agent, as well as for its ability to inhibit the growth of certain bacteria and fungi. Additionally, 2-morpholin-4-ylacetohydrazide has been investigated for its potential as a corrosion inhibitor in different industries. Its chemical structure and properties make it a promising candidate for further research and potential applications in various fields.

InChI:InChI=1/C6H13N3O2/c7-8-6(10)5-9-1-3-11-4-2-9/h1-5,7H2,(H,8,10)

Upstream product

• 3235-82-3 N-morpholylacetic acid ethyl ester 
• 35855-10-8 methyl 2-morpholin-4-ylacetate 

Downstream Products

• 92034-92-9 1-(morpholin-4-yl-acetyl)-4-phenyl-semicarbazide 
• 72285-43-9 4-(3-chloro-phenyl)-1-(morpholin-4-yl-acetyl)-thiosemicarbazide 
• 72285-44-0 4-(2-methoxy-phenyl)-1-(morpholin-4-yl-acetyl)-thiosemicarbazide 
• 72285-45-1 4-(3-methoxy-phenyl)-1-(morpholin-4-yl-acetyl)-thiosemicarbazide 
• 72285-40-6 1-(morpholin-4-yl-acetyl)-4-o-tolyl-thiosemicarbazide 
• 72285-41-7 1-(morpholin-4-yl-acetyl)-4-m-tolyl-thiosemicarbazide 
• 5956-95-6 morpholin-4-yl-acetic acid (2-oxo-2-phenyl-ethylidene)-hydrazide 
• 7037-21-0 morpholin-4-yl-acetic acid (2-biphenyl-4-yl-2-oxo-ethylidene)-hydrazide 
• 72606-35-0 morpholin-4-yl-acetic acid (2,3,5,6-tetramethyl-benzylidene)-hydrazide 
• 7037-26-5 morpholin-4-yl-acetic acid [2-oxo-2-(4-phenoxy-phenyl)-ethylidene]-hydrazide 
• 6592-87-6 morpholin-4-yl-acetic acid [2-oxo-2-(4-phenylsulfanyl-phenyl)-ethylidene]-hydrazide 
• 72285-42-8 4-(2-chloro-phenyl)-1-(morpholin-4-yl-acetyl)-thiosemicarbazide 
• 72285-46-2 4-(4-iodo-phenyl)-1-(morpholin-4-yl-acetyl)-thiosemicarbazide 
• 72285-48-4 5-morpholin-4-ylmethyl-4-m-tolyl-2,4-dihydro-[1,2,4]triazole-3-thione 

Relevant articles and documents

Synthesis of novel Schiff bases and azol-β-lactam derivatives starting from morpholine and thiomorpholine and investigation of their antitubercular, antiurease activity, acethylcolinesterase inhibition effect and antioxidant capacity

In this study, new Schiff bases and β-lactam derivatives containing morpholine and thio morpholine nuclei were synthesized. Antimicrobial, antioxidant, antimicrobial and antioxidant properties of all synthesized compounds were investigated and highly effe

1,8-Naphthyridines IX. Potent anti-inflammatory and/or analgesic activity of a new group of substituted 5-amino[1,2,4]triazolo[4,3-a][1,8]naphthyridine-6- carboxamides, of some their Mannich base derivatives and of one novel substituted 5-amino-10-oxo-10H-pyrimido[1,2-a][1,8]naphthyridine-6-carboxamide derivative

A new group of 5-(alkylamino)-9-isopropyl[1,2,4]triazolo[4,3-a][1,8] naphthyridine derivatives bearing a CONHR group at the 6-position (1c-g), designed to obtain new effective analgesic and/or anti-inflammatory agents, were synthesized and tested along with three new 9-alkyl-5-(4-alkyl-1-piperazinyl)- N,N-diethyl [1,2,4]triazolo[4,3-a][1,8]naphthyridine-6-carboxamides (2b-d). Besides, a new class of analogues of compounds 1 and 2, bearing a Mannich base moiety at the 9-position (12a-d), as well as the novel N,N-diethyl-5- (isobutylamino)-8-methyl-10-oxo-10H-pyrimido[1,2-a][1,8]naphthyridine-6- carboxamide (15) were prepared and tested. Compounds 1c-g exhibited very interesting anti-inflammatory properties in rats, whereas compounds 2b-d and 15 proved to be endowed with prevalent analgesic activity frequently associated with sedative effects in mice. On the contrary, the Mannich bases 12a-d resulted inactive. The most effective (80% inhibition of oedema) and potent (threshold dose 1.6 mg kg-1 with 31% inhibition of oedema) anti-inflammatory compound 1d did not show gastrolesive effects following 100 mg kg-1 oral administration in rats.

Substituted imidazo-[1,5-a][1,2,4]triazolo[1,5-d][1,4] benzodiazepine derivatives

The present invention is concerned with substituted imidazo[1,5-a][1,2,4]triazolo[1,5-d][1,4]benzodiazepine derivatives of the following formula wherein the definition of substituents is described in the claims. This class of compounds shows high affinity