77035-44-0Relevant articles and documents
HETEROCYCLIC COMPOUNDS FOR THE INHIBITION OF PASK
-
Page/Page column 25, (2012/11/08)
Disclosed herein are new heterocyclic compounds and compositions and their application as pharmaceuticals for the treatment of disease. Methods of inhibiting PAS Kinase (PASK) activity in a human or animal subject are also provided for the treatment of diseases such as diabetes mellitus.
A convenient protocol for the synthesis of hindered aryl malononitriles
Schnyder, Anita,Indolese, Adriano F.,Maetzke, Thomas,Wenger, Jean,Blaser, Hans-Ulrich
, p. 3167 - 3169 (2008/02/13)
A technically feasible method has been developed for the synthesis of variety of aryl malononitriles in high yields (70-95%) using the palladium-catalyzed coupling reaction of malononitrile with aryl bromides and chlorides, respectively. The influence a s